arrow_backToday
Archive
1689 items, newest first. Nothing is deleted.
Saturday, 12 September 2026
When the Cure Turns Into a Culprit: Mesalamine and the Eosinophilic Lung
In UC patients on mesalamine who develop cough, fever or dyspnea, consider drug-induced eosinophilic lung disease and stop the drug rather than escalating therapy.
Gastroenterology · Cureus · 12 Sept
Hypothyroidism Versus Hyperthyroidism in Patients With Abnormal Uterine Bleeding: An Observational Study
Hypothyroidism in 33 (13.1%), hyperthyroidism in 8 (3.2%). Irregular menstruation in 6 (75.0%) hyperthyroid versus 9 (27.3%) hypothyroid, p=0.012; menorrhagia in 18 (54.5%) hypothyroid versus 2 (25.0%) hyperthyroid.
Obstetrics & Gynaecology · Cureus · 12 Sept
Quantifying Diagnostic Misclassification and Inpatient Mortality Determinants in Scrub Typhus: A Systematic Review and Interaction Meta-Analysis of Acute Undifferentiated Febrile Illness (AUFI) Cohorts in India
Pooled scrub typhus prevalence 14.60% (95% CI 11.27-18.71); high-rigor assays 17.40% versus rapid ICT or Weil-Felix 11.90% (p = 0.024); pooled inpatient mortality 4.92% (95% CI 2.98-7.95)
General Medicine · Cureus · 12 Sept
Maternal Delivery Outcomes Associated With Acute Sickle Cell Crisis: A National Inpatient Analysis
Severe preeclampsia, eclampsia or HELLP occurred in 27.9% with crisis versus 6.8% without (adjusted OR 4.63; 95% CI 2.43-8.85). Cesarean delivery adjusted OR 2.18 (95% CI 1.30-3.68).
Obstetrics & Gynaecology · Cureus · 12 Sept
Music in the Operating Room: Impact on Team Communication, Focus, and Monitoring Patient Safety
70.3% (n=97) reported mood benefits, but 33% (n=37) impaired communication, 8% (n=11) impaired concentration and 11.6% (n=16) impaired safety monitoring; 66.2% (n=49) said appropriateness varied by surgical phase.
Anaesthesiology · Cureus · 12 Sept
Granulomatous Interstitial Nephritis Associated With Adalimumab Therapy in a Patient With Rheumatoid Arthritis: A Case Report
Renal biopsy showed granulomatous interstitial nephritis. Adalimumab was stopped and steroids started; kidney function improved.
General Medicine · Cureus · 12 Sept
Recurrent Great Saphenous Vein Reflux After Prior Endovenous Laser Therapy: Diagnostic and Management Challenges in Chronic Venous Insufficiency
Duplex ultrasound showed near-continuous reflux in the proximal GSV with incompetent accessory and perforator veins, indicating recurrence driven by untreated tributaries rather than the ablated segment alone.
General Surgery · Cureus · 12 Sept
Shared Decision-Making and Decision Support in Advanced Chronic Kidney Disease: A Systematic Review of Models, Treatment Pathways, and Patient-Centered Outcomes
Structured decision aids for dialysis-versus-conservative-care choices may improve modality selection and patient-reported outcomes; this review maps which models have evidence behind them.
General Medicine · Cureus · 12 Sept
Racial and Ethnic Disparities in Receipt of Behavioral Treatment Among Children With Autism Spectrum Disorder in the United States
564 of 790 (71.4%) received behavioural treatment. Non-Hispanic Black children were less likely than White children to receive it (adjusted OR 0.47, 95% CI 0.28-0.79). Asian, Hispanic and multiracial differences were not significant.
Paediatrics · Cureus · 12 Sept
India crosses 80 lakh HPV vax in nationwide cervical cancer prevention drive
With 80 lakh girls aged 14 now vaccinated, HPV coverage is becoming routine in India — expect more questions from parents and fewer missed opportunities to offer the vaccine.
Obstetrics & Gynaecology · ETHealthworld · 12 Sept
Efficacy and safety of mitapivat in adults with transfusion-dependent α-thalassaemia or β-thalassaemia (ENERGIZE-T): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial.
Transfusion reduction response occurred in 52 (30%) of 171 on mitapivat versus 11 (13%) of 87 on placebo; adjusted difference 18 percentage points (95% CI 8-27; p=0·0003).
General Medicine · Lancet · 12 Sept
Tambotatug Pelitecan in Small-Cell Lung Cancer after Platinum-Based Therapy.
Median overall survival 13.3 vs 9.4 months (HR 0.46, 95% CI 0.35-0.62; P<0.001). Median progression-free survival 7.4 vs 2.8 months. Objective response 59.1% vs 9.7%. Grade 3+ adverse events 55.4% vs 77.9%.
Oncology · NEJM · 12 Sept
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Based Genome Editing in Inherited Cardiovascular Diseases: Therapeutic Advances, Emerging Editing Platforms, and Translational Challenges
No trial results are reported. Preclinical work corrected MYBPC3 and MYH7 in HCM, targeted TTN, RBM20 and LMNA in DCM, restored ion channel function, and modulated PCSK9, LDLR and ANGPTL3.
Cardiology · Cureus · 12 Sept
Friday, 11 September 2026
Systematic Review and Meta-Analysis on Central and/or Peripheral Nervous System Demyelination in Patients Treated With Tumor Necrosis Factor Alpha (TNF-α) Inhibitors
Pooled random-effects estimates: RR 1.46 (95% CI 1.09-1.95) for CNS demyelination and RR 2.00 (95% CI 1.19-3.38) for PNS demyelination.
Neurology · Cureus · 11 Sept
Cardiac Metastasis From Lung Cancer: A Hidden Cardioembolic Source of Acute Ischemic Stroke
Brain MRI showed multiple acute ischemic infarcts in the left middle cerebral artery territory; cardiac imaging found a left ventricular mass suggestive of metastasis. She died one year later.
Neurology · Cureus · 11 Sept
Benchmarking Drug Library Compliance and Alert Rates in Smart Infusion Pumps: A Multicenter Retrospective Study
Overall DL compliance was 95.9%, mean alert rate 33.3% (±12.20), override rate 96.4%, and one good catch per 34.5 DERS infusions. No significant differences between compliance groups.
Anaesthesiology · Cureus · 11 Sept
Jugular Venous Compression via Soft Cervical Collar in Shunt-Refractory Low-Pressure Hydrocephalus: A Report of Two Cases
Third ventricular width decreased from 13 to 8 mm in case 1 and 13 to 4 mm in case 2; ventriculomegaly recurred on collar cessation and resolved on reapplication in case 1
Neurology · Cureus · 11 Sept
Definium LSD drug goes 3 for 3 with another pivotal anxiety trial win
A third positive phase 3 supports LSD-assisted therapy as a regulated option for anxiety, though psychedelic protocols need supervised dosing and monitoring your clinic may not have.
Psychiatry · Fierce Biotech · 11 Sept
Polyvascular Atherosclerotic Disease: A Narrative Review of the Role of Systematic Bedside Vascular Examination
No original data or effect estimates are reported; the review argues that abnormal bedside findings should prompt selective ABI, duplex, CTA, MRA or cardiac testing rather than indiscriminate imaging.
Cardiology · Cureus · 11 Sept
Cullinan, Taiho showcase 6-month survival benefit in phase 3 trial for advanced lung cancer
A six-month frontline survival gain in advanced NSCLC offers your EGFR-mutant patients a new first-line option beyond current standard combinations.
Oncology · Fierce Biotech · 11 Sept
Owkin, Servier ink oncology R&D deal to guide discovery and trial design
AI-guided trial design could sharpen oncology trial enrolment and biomarker selection, but no clinical data yet shows it improves patient outcomes.
Oncology · Fierce Biotech · 11 Sept
Beyond clinical endpoints: Rethinking ALS drug development through disease biology
If biology-driven endpoints replace survival and ALSFRS-R in ALS trials, the drugs you can offer patients may change faster than current approval standards allow.
Neurology · Fierce Biotech · 11 Sept
ARPA-H launches $63M effort to build FDA-authorized AI agents for heart failure care
Autonomous AI agents for heart failure could soon reach your clinic with FDA oversight, so watch how these tools are validated before adoption.
Cardiology · Fierce Healthcare · 11 Sept
PHTI report finds limited impact from virtual kidney care solutions, prompting industry pushback
Before referring CKD patients to virtual kidney programmes, note this review found limited evidence of benefit, though vendors dispute the methodology.
General Medicine · Fierce Healthcare · 11 Sept
The future of RAS inhibitors
RAS inhibitors are moving beyond one approved drug for pancreatic cancer, so expect more targeted options for KRAS-mutant tumours in coming years.
Oncology · Fierce Biotech · 11 Sept
FDA delays approval decision for Exelixis' tyrosine kinase inhibitor in colorectal cancer
A potential oral option added to atezolizumab for metastatic colorectal cancer is pushed back, so keep current regimens unchanged for now.
Oncology · Fierce Biotech · 11 Sept
Tricuspid Stenosis Due to Cardiac Sarcoma
Echocardiography showed a large right atrial mass obstructing tricuspid inflow plus significant pericardial effusion; resection confirmed biphasic synovial sarcoma. Postoperatively he developed atrial flutter with left ventricular dysfunction needing cardioversion.
Cardiology · Cureus · 11 Sept
Variability of Nutritional Status During Hematopoietic Stem Cell Transplantation and Its Association With Clinical Outcomes: An Ambispective Observational Study From India
Mean weight fell from -1.80% at day 0 to -7.65% at day +30. At day +60, weight loss was greater with viral infections (-14.7% vs -5.4%; p=0.03) and stays >36 days (-14.6% vs -5.3%; p=0.025).
Oncology · Cureus · 11 Sept
BioNTech sets survival standard in hard-to-treat cancer ahead of pivotal readout
In relapsed lung cancer, gotistobart achieved 18.5-month median overall survival, exceeding current standard-of-care benchmarks; confirmatory pivotal data are still pending.
Oncology · Fierce Biotech · 11 Sept
STAT+: An AI tool aims to catch harder-to-detect heart attacks in EKGs
An AI ECG reader cleared to flag occult coronary occlusion could catch NSTEMI and posterior MI patterns that clinicians and standard algorithms miss.
Cardiology · STAT News — Health Tech · 11 Sept
Lower Extremity Salvage Through Dextranomer Debridement and Evolution Toward a Functional Pincer in a Diabetic Foot: Experience in Rural Surgery
Serial topical dextranomer microbeads controlled exudate and fibrin, halted necrotic progression, and produced a clean granulating wound bed; the patient avoided proximal amputation after an 18-day hospital stay.
General Surgery · Cureus · 11 Sept
Evaluation of Tooth Shade Selection With Conventional Methods and Artificial Intelligence-Integrated Methods: A Comparative Study
Exact shade agreement 78.2% with AI versus 49.1% conventional; Cohen's kappa 0.75 vs 0.43; accuracy 87.3% vs 74.5%; mean CIEDE2000 1.42 vs 1.76.
Medicine · Cureus · 11 Sept
Hyperglycemic Hyperosmolar State As the Initial Presentation of Type 1 Diabetes Mellitus in an Adolescent: A Case Report
Glucose exceeded 1,000 mg/dL with hyperosmolality, dehydration and only mild acidosis; treatment caused marked glucose swings needing repeated insulin and dextrose titration.
Paediatrics · Cureus · 11 Sept
Effectiveness and Patient Compliance of a Needle-Free Injection System in Controlled Ovarian Stimulation in IVF Cycles: A Real-World, Investigator-Initiated, Retrospective, Multicenter, Observational Study
Mean oocytes retrieved 13.4 ± 6.2 (r-FSH) versus 6.1 ± 7.6 (r-FSH+hMG); metaphase II oocytes 11.0 ± 5.4 versus 4.8 ± 6.3. Pain score 1.2 ± 1.3 for r-FSH, 3.6 ± 2.2 for hMG.
Obstetrics & Gynaecology · Cureus · 11 Sept
Safety and Recovery Profile of Propofol-Based Intravenous Sedation for Endoscopic Retrograde Cholangiopancreatography in Adults: A Prospective Single-Center Observational Study
No oxygen desaturation or intubation (0/100, 95% CI 0-3.6). Airway maneuvers and procedural interruption in 5/100 (5%), PONV in 4/100 (4%). Median recovery 5 minutes.
Anaesthesiology · Cureus · 11 Sept
Neurosurgical Outcomes of Epilepsy Surgery Between 2017 and 2025: A Retrospective ESSQ-19 Study From a Tertiary Care Center
ESSQ-19 summary score was 84.1±21.7. Surgical complication domain scored 89.2±21.1 and seizure control 85.0±27.6, while psychosocial domain scored lower at 79.9±24.1.
Neurology · Cureus · 11 Sept
GSK’s Hansoh-partnered ADC lays down marker for lung cancer scrap with Merck
A new ADC achieved 18.5-month median overall survival in phase 3 lung cancer, potentially adding a treatment option beyond current standard regimens.
Oncology · Fierce Biotech · 11 Sept
Preservation of Non-nidal Medial Veins During Microsurgical Resection of Cerebral Arteriovenous Malformations: Technical Considerations and Early Clinical Outcomes
Complete angiographic nidus eradication in all 16 patients, no perioperative mortality, and mRS 0-2 in 14 patients (87.5%). No delayed venous infarction or haemorrhagic transformation occurred.
Neurology · Cureus · 11 Sept
Early Prognostic Value of the Freiburg Index of Post-Transjugular Intrahepatic Portosystemic Shunt Survival in Patients With Hepatocellular Carcinoma Undergoing Liver Transplantation
Pre-transplant FIPS may flag HCC patients at higher risk of early post-transplant death, helping you refine waitlist and perioperative counselling.
Gastroenterology · Cureus · 11 Sept