Archive

Ayble Health banks $16M series A to expand AI-driven precision digestive, autoimmune healthcare

A funded AI platform for GI and autoimmune care may reach your patients through their insurers, so know what it offers before they ask.

Gastroenterology · Fierce Healthcare · 15 Sept

Combination of Technologies in Body Contouring: Evidence Mapping and a Decision-Making Algorithm

Surgical-energy pairings, chiefly radiofrequency-assisted and helium plasma-assisted liposuction, gave the most consistent additive skin retraction with acceptable safety; non-invasive pairings gave measurable but modest fat and muscle gains.

General Surgery · Cureus · 15 Sept

Uterocervical Angle (UCA) Combined With the Bishop Score as a Predictor for Successful Induction of Labor in Term Pregnancy: A Prospective Observational Study

UCA ≥107.25° gave 57.3% sensitivity and 72.8% specificity; Bishop score ≥4 gave 59.3% and 72.8%. Combined criteria (UCA ≥107.25° or Bishop score ≥4) reached 80.6% sensitivity and 64.1% specificity.

Obstetrics & Gynaecology · Cureus · 15 Sept

Memantine-Induced Sialorrhea: A Rare Adverse Reaction and Review of Pathophysiological Mechanisms

If a dementia patient on memantine develops unexplained drooling, consider the drug as the cause rather than assuming progression or a new neurological deficit.

Neurology · Cureus · 15 Sept

Prevalence of Mild Autonomous Cortisol Secretion Among Patients With Adrenal Incidentaloma and Its Association With Metabolic Abnormalities: A Hospital-Based, Analytical, Cross-Sectional Study

MACS in 95 (25.0%). Adjusted associations: obesity aOR 1.85 (1.09-3.14), diabetes aOR 1.68 (1.01-2.80), metabolic syndrome aOR 1.82 (1.11-2.98); lesion size aOR 1.38 per cm (1.14-1.67).

Endocrinology · Cureus · 15 Sept

Fatal Pulmonary Tumor Thrombotic Microangiopathy Associated With Disseminated Carcinomatosis of the Bone Marrow From Occult Gastric Cancer: An Autopsy-Confirmed Case

Bone marrow biopsy confirmed disseminated carcinomatosis; autopsy showed type 4 gastric adenocarcinoma with pulmonary tumor microemboli and fibrocellular intimal proliferation causing fatal respiratory failure.

Oncology · Cureus · 15 Sept

Phenotypic Characterization of Multidrug-Resistant Pseudomonas aeruginosa Isolated From Patients With Ventilator-Associated Pneumonia: Insights Into Resistance Mechanisms and Biofilm Formation

Complete resistance to piperacillin and imipenem (100% each), piperacillin-tazobactam and meropenem 98.08% each; aztreonam most susceptible (83.65%). MBL production in 80 (76.92%), ESBL in 7 (6.73%). Biofilm in 54 (51.92%) by tube method.

General Medicine · Cureus · 15 Sept

Prevention and Management of Pediatric Sensitive Skin Conditions in India: A Modified Delphi Consensus

Experts unanimously agreed diaper dermatitis, xerosis and atopic dermatitis are the most prevalent paediatric sensitive skin conditions; emollients were recommended as the cornerstone of management, with colloidal oatmeal emollients favoured in xerosis and atopic dermatitis.

Paediatrics · Cureus · 15 Sept

Pediatric Rosai-Dorfman-Destombes Disease: From Isolated Cervical Lymphadenopathy to Multisystem Disease

Consider RDD in a child with persistent cervical lymphadenopathy, since the same disease can progress from a single node to multisystem involvement.

Paediatrics · Cureus · 15 Sept

A Rare Encounter With Peripheral Dentinoma: Clinicopathological Insights

Microscopy showed a disorganized mass of tubular dentin with sclerotic, atubular eosinophilic dentinoid areas, confirming dentinoma; the preoperative provisional diagnosis was foreign body.

Medicine · Cureus · 15 Sept

Congenital Bile Acid Synthesis Defect Type 2 Mimicking Biliary Atresia: A Case Report of Delta-4-3-Oxosteroid 5-Beta-Reductase Deficiency in a Two-Month-Old Infant

Urine LC-MS/MS showed trace primary bile acids with Δ4-3-oxo intermediates; NGS confirmed CBASD type 2. Liver biopsy showed giant cell hepatitis without ductal proliferation, excluding BA.

Paediatrics · Cureus · 15 Sept

Evvy raises $40M to expand precision medicine for vaginal health

A clinician-reviewed at-home vaginal microbiome test with treatment plans may reach your patients before you do; know what it reports and its limits.

Obstetrics & Gynaecology · Fierce Healthcare · 15 Sept

STAT+: Medicare’s AI prior authorization pilot was rushed and full of problems, new documents reveal

If AI-driven prior authorization spreads, expect more denials and delays for your Medicare patients; document necessity carefully and appeal with clinical detail.

General Medicine · STAT News — Health Tech · 15 Sept

Gastric Ischemia Secondary to Atherosclerotic Disease: A Case Report and Literature Review

CT angiography showed near-complete coeliac trunk occlusion, 3-cm severe superior mesenteric artery stenosis with near-occlusion, and 40% inferior mesenteric artery stenosis. Stenting resolved symptoms and achieved complete endoscopic mucosal healing.

Gastroenterology · Cureus · 15 Sept

Comparison of Sugammadex and Neostigmine for Reversal of Vecuronium-Induced Neuromuscular Blockade in Pediatric Patients: A Prospective Randomized Study

Median time to TOF ≥0.9 was 70 (65-108) vs 252 (240-280) seconds, and to TOF 1.0 was 85.5 (75-142) vs 272 (255-304) seconds, sugammadex vs neostigmine, p = 0.001.

Anaesthesiology · Cureus · 15 Sept

Medication Adherence in Patients With Glaucoma and Determinants of Treatment Adherence: A Cross-Sectional Study

Full adherence reported by 55.8% (43/77). Adherence associated with glaucoma severity (p=0.002), education (p<0.001), income (p<0.001), clinician-patient communication (p<0.001), follow-up (p=0.03), motivation (p<0.001), memory (p<0.001), drop difficulty (p=0.001), side effects (p<0.001)

Ophthalmology · Cureus · 15 Sept

Persistent Diarrhea Due to Cyclospora cayetanensis Diagnosed by Multiplex GI PCR in a Patient With HIV: A Case Report

Conventional bacterial stool culture identified no enteric pathogen and ciprofloxacin did not help; multiplex GI PCR detected C. cayetanensis, treated with TMP-SMX 160/800 mg twice daily for 10 days

Gastroenterology · Cureus · 15 Sept

Evaluation of Alterations in Serum Uric Acid Levels in Newly Diagnosed Overt Thyroid Dysfunction: A Prospective Observational Study From a Tertiary Care Center

Uric acid was higher in thyroid dysfunction than controls (5.62 ± 2.28 vs. 4.46 ± 1.13 mg/dL, p < 0.001); creatinine was lower (0.86 ± 0.16 vs. 0.92 ± 0.22 mg/dL, p = 0.010). Uric acid AUC 0.642, cutoff 4.05 mg/dL, 71.3% sensitivity.

Endocrinology · Cureus · 15 Sept

Effectiveness of Virtual Reality-Based Rehabilitation on Balance, Gait, and Functional Independence in Patients With Parkinson’s Disease: Implications for Healthy Longevity

Berg Balance Scale improved +8.97 versus +4.52 points, TUG −3.51 versus −1.79 seconds, gait speed +0.234 versus +0.111 m/s; 108 of 125 (86.4%) versus 34 of 125 (27.2%) reached lower fall-risk category.

Neurology · Cureus · 15 Sept

After rejection, FDA approves Telix’s Pixclara, the first FET-PET imaging drug for brain cancer

FET-PET distinguishes true tumour progression from post-treatment pseudoprogression in glioma, sparing patients unnecessary biopsy or therapy change.

Oncology · Fierce Biotech · 15 Sept

J&J’s Contineum-partnered depression drug flunks another phase 2 test

A second phase 2 miss for JNJ-5120 means this mechanism is unlikely to reach your treatment-resistant depression patients; keep current options.

Psychiatry · Fierce Biotech · 15 Sept

Modern Obesity Treatment: Efficacy, Safety, and Future Directions of GLP-1 (Glucagon-Like Peptide-1) and GIP (Glucose-Dependent Insulinotropic Polypeptide) Receptor Agonists

Liraglutide established GLP-1 agonism for weight management; semaglutide gave greater, more sustained weight reduction; tirzepatide produced greater weight loss than semaglutide in direct comparative studies.

Endocrinology · Cureus · 15 Sept

Indian AI platform for cancer care featured in BRICS health journal

AIIMS-built decision support for cancer care is now peer-visible, so Indian oncologists may soon see it offered in their own workflows rather than imported tools.

Oncology · ETHealthworld · 15 Sept

Interrater Reliability of the Modified Tuck Jump Assessment Scored by Physical Therapy Students

Total score interrater reliability was excellent (ICC(2,1) = 0.868; 95% CI, 0.775-0.924), but item-level linear-weighted kappa ranged from 0.30 to 0.78, with six of 10 items not reaching substantial agreement.

Orthopaedics · Cureus · 15 Sept

Virological and metabolic outcomes after switching to dolutegravir or rilpivirine in virologically suppressed adults with HIV in Thailand: an open-label, randomised, controlled, non-inferiority trial.

In suppressed patients on efavirenz, switching to dolutegravir or rilpivirine kept viral suppression but differed in weight and metabolic effects, informing which switch suits whom.

General Medicine · Lancet regional health. Southeast Asia · 15 Sept

Broadly neutralizing antibodies in adult males living with HIV undergoing analytical treatment interruption: secondary and exploratory outcomes of the phase II randomized controlled RIO trial.

Rebounding virus showed significant selection for resistance to 10-1074-LS but not 3BNC117-LS. Greater baseline reservoir sensitivity to autologous antibodies and 10-1074 correlated with longer time to rebound.

General Medicine · Nature Medicine · 15 Sept

Age-associated loss of lymphatic vessels promotes cardiac inflammation.

Aging lowered cardiac lymphatic density in humans and mice, with immune infiltration, fibrinogen and amyloid accumulation and myocardial edema; Vegfc overexpression or Il33 silencing restored lymphatic density and homeostasis in aged hearts.

Cardiology · Nature cardiovascular research · 15 Sept

Evaluation and Management of Anemia in Chronic Kidney Disease: Synopsis of the Kidney Disease: Improving Global Outcomes 2026 Clinical Practice Guideline.

Eight graded recommendations: iron guided by transferrin saturation and ferritin, intravenous iron preferred over oral in hemodialysis, correctable causes addressed first, ESA preferred over HIF-PHI first-line, upper Hb target below 11.5 g/dL.

General Medicine · Annals · 15 Sept

Cryo-EM structures of Candida albicans chitin synthase Chs1 reveal a druggable translocation channel.

DA binds the chitin translocation channel, occluding polymer extrusion, and shows potent synergy with nikkomycin Z against C. albicans and C. auris.

General Medicine · Nature microbiology · 15 Sept

A Synopsis of the 2025 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guideline for Lipid Management for Cardiovascular Disease Risk Reduction.

New: PREVENT calculator for primary prevention risk estimation; routine lipid monitoring no longer discouraged; coronary artery calcium for intermediate-to-high risk with uncertainty; one-time lipoprotein(a) testing; moderate-intensity statins for adults with HIV even at low 10-year risk.

Cardiology · Annals · 15 Sept

On-premise medical AI agents for reliable clinical decision-making.

Accuracy was 90.04% on the seven-disease task and 83.8% on the four-disease task. Diagnostic behavioural consistency best predicted correctness (AUC 0.860; 0.875 under stress testing). At threshold 0.90, 49.4% of cases retained at 98.9% accuracy.

General Medicine · Nature Medicine · 15 Sept

The Potential Therapeutic Effects of Testosterone on Sarcopenia: A Thorough Systematic Review

Testosterone may modestly improve muscle mass and strength in older adults with sarcopenia, but evidence on falls and function remains weak — counsel patients before prescribing.

Endocrinology · Cureus · 15 Sept

As ‘cultural weight’ of a psychedelic approval looms, FDA hearing focuses on access and safety

If MDMA-assisted therapy is approved, you will need to know referral pathways, monitoring requirements and how to counsel patients about supervised psychedelic treatment.

Psychiatry · Fierce Healthcare · 14 Sept

As ‘cultural weight’ of a psychedelic approval looms, FDA hearing focuses on access and safety

If MDMA-assisted therapy is approved, you will need to know its monitoring requirements and how patients access it, since real-world safety data remain limited.

Psychiatry · Fierce Biotech · 14 Sept

Bias Mitigation Across the Healthcare Artificial Intelligence Lifecycle: A Structured Narrative Review

No primary quantitative result; the review catalogues sampling, adversarial learning, subpopulation techniques, and new model structures, and proposes a lifecycle protocol spanning data acquisition to deployment

General Medicine · Cureus · 14 Sept

GE HealthCare launches AI-driven operations system

If it reliably flags bed and theatre crunches 72 hours out, it could change how you schedule admissions and elective lists.

Medicine · Fierce Healthcare · 14 Sept

Dexmedetomidine Versus Dexamethasone as Adjuvants to Bupivacaine for Wound Infiltration After Caesarean Section Under Spinal Anaesthesia

Tramadol use over the first day was lowest with dexmedetomidine (87.33 ± 17.40 mg), then dexamethasone (129.43 ± 15.61 mg), then bupivacaine alone (150.33 ± 14.59 mg); P<0.0001.

Anaesthesiology · Cureus · 14 Sept

Molecular Etiology and Mortality Risk Stratification of Non-SARS-CoV-2 Severe Acute Respiratory Infection in a Predominantly Pediatric Cohort: A Retrospective Study From a Tertiary Care Hospital in North India

In North Indian children with non-COVID SARI, the ViVI severity score may help you flag those at higher mortality risk early and target escalation.

Paediatrics · Cureus · 14 Sept

Perfusion Index as a Predictor of Hypotension Following Spinal Anesthesia in Below-Umbilical Surgeries

21 of 92 (22.8%) developed hypotension. Baseline PI was higher in those who did (4.38±1.67 vs 1.51±0.53, P<0.001). PI ≥2.53 gave 100% sensitivity, 98.6% specificity, AUC 0.999.

Anaesthesiology · Cureus · 14 Sept

Potential new TB vaccines could save millions of lives: Gavi

If new TB vaccines reach India's immunisation schedule, they could cut a disease you still diagnose weekly in young adults and children.

General Medicine · ETHealthworld · 14 Sept