Archive

Bacteroides fragilis Empyema Secondary to Ruptured Pyogenic Liver Abscess: A Rare Cause of Septic Shock

CT showed a 9.05 × 4.37 cm collection behind the right hepatic lobe and right pleural effusion; ultrasound confirmed a 9.6 cm hepatic abscess. Pleural and abscess cultures both grew Bacteroides fragilis

Gastroenterology · Cureus · 17 Sept

An Alternative Approach to Adult One-Lung Ventilation Using a Standard Single-Lumen Endotracheal Tube

No quantitative outcomes reported; the abstract describes the technique and its indications only, with no ventilation, oxygenation or surgical data given.

Anaesthesiology · Cureus · 17 Sept

Prevalence and Severity of Hepatic Steatosis and Fibrosis Across Glycemic Categories Among Patients Attending a Tertiary Care Hospital: A FibroScan-Based Cross-Sectional Study

Severe steatosis (S3) in 2.4% nondiabetic, 6.9% prediabetic, 18.7% T2DM; adjusted aOR 2.22 (1.26-3.94) for prediabetes and 3.58 (1.58-8.14) for T2DM. Fibrosis distribution did not differ (p = 0.480).

Endocrinology · Cureus · 17 Sept

Physiotherapy Management of Computer Vision Syndrome and Associated Musculoskeletal Dysfunction in Young Adults: A Systematic Review of Evidence-Based Rehabilitation Approaches

For young patients with screen-related eye strain and neck or shoulder pain, the evidence supports combined ergonomic and postural physiotherapy rather than eye drops alone.

Ophthalmology · Cureus · 17 Sept

Beyond Pneumonia: A Case of Steroid-Responsive Pulmonary Eosinophilia With Atypical p-ANCA Positivity

When opacities persist on antibiotics, consider eosinophilic lung disease and trial steroids rather than escalating antimicrobials.

General Medicine · Cureus · 17 Sept

ARPA-H launches SPECTRA program, new autism research initiative

A US-funded push to standardise early autism risk detection and referral could shape the screening pathways and trial options you discuss with families.

Paediatrics · Fierce Biotech · 17 Sept

False-Negative Ligamentum Teres Tendon Sampling for the Detection of Systemic Amyloidosis

A negative ligamentum teres biopsy does not exclude transthyretin amyloidosis; sample ligamentum flavum or flexor tenosynovium instead when carpal tunnel and spinal stenosis coexist.

Orthopaedics · Cureus · 17 Sept

Sex Differences in Early Functional Outcomes After Acute Stroke: A Retrospective Cohort Study at a United Kingdom Tertiary Stroke Centre

Unadjusted, women had worse discharge mRS (common OR 1.34, 95% CI 1.10–1.64). After adjusting for age and pre-stroke mRS the association fell to 0.95 (95% CI 0.77–1.16) and fully adjusted 0.94 (0.76–1.16).

Neurology · Cureus · 17 Sept

Plasma Cystatin C as a Marker of Acute-on-Chronic Liver Failure and 28-Day Mortality in Patients With Acutely Decompensated Liver Cirrhosis: A Prospective Observational Study

Cystatin C may flag renal failure and 28-day death risk in decompensated cirrhosis better than creatinine, which overestimates GFR in these patients.

Gastroenterology · Cureus · 17 Sept

Improving Arterial Blood Gas Sampling Practice in the Emergency Department: A Two-Cycle Clinical Audit

Using venous gases to screen COPD exacerbations before arterial puncture can cut a painful, repeated invasive procedure in your emergency patients.

General Medicine · Cureus · 17 Sept

A Systematic Review and Meta-Analysis: Does Molecular Hydrogen Exert Radioprotective Effects Without Compromising the Antitumor Efficacy of Radiotherapy or Concurrent Chemoradiotherapy?

Tumour response was unchanged with molecular hydrogen versus control: RR 0.98 (95% CI 0.83-1.15); randomised trials only, RR 0.99 (95% CI 0.84-1.17). Narrative synthesis reported reduced radiation-induced toxicities.

Oncology · Cureus · 17 Sept

Trends in the Frequency of Severe Maternal Morbidity Among American Indian and Alaska Native Individuals at Two Major Hospitals in the East Valley, Arizona

AI/AN individuals had the highest cumulative SMM rate (4.12%; 64 cases among 1,554 deliveries), rising from 1.13% in 2020 to 6.17% in 2025 — the only group with a significant trend (0.848 percentage points per year; p = 0.0415).

Obstetrics & Gynaecology · Cureus · 17 Sept

Molecular Role of Carbohydrates in Acne and Seborrheic Dermatitis

In acne, high GI/GL plausibly drives hyperinsulinemia, IGF-1, mTORC1 activation and inflammation, but clinical dietary trials remain inconsistent. No direct dietary-glycemic evidence exists for seborrheic dermatitis.

Medicine · Cureus · 17 Sept

From Unexplained Iron-Deficiency Anaemia to Ileo-Ileal Intussusception: A Case Report of Primary Small Bowel Leiomyosarcoma

CT showed ileo-ileal intussusception; laparoscopic segmental small bowel resection found a spindle-cell leiomyosarcoma with mucosal ulceration. Anaemia resolved by two-month follow-up without transfusion; mild residual iron deficiency remained.

Gastroenterology · Cureus · 17 Sept

Spontaneous Retrobulbar Hematoma During a Hypertensive Crisis Managed Without Surgical Decompression: A Case Report

Visual acuity recovered to 10/10 (20/20), intraocular pressure fell to 18 mmHg, proptosis regressed and motility normalised after IV methylprednisolone and antihypertensives; hematoma resolved completely at four weeks.

Ophthalmology · Cureus · 17 Sept

Renal-Limited Thrombotic Microangiopathy Presenting as Acute on Chronic Kidney Failure in the Absence of Schistocytosis

Peripheral smear, autoimmune serologies and skin biopsy were unrevealing; only kidney biopsy showed TMA. She progressed to stage 5 CKD requiring peritoneal dialysis.

General Medicine · Cureus · 17 Sept

DPHARM: How to address the clinical trial enrollment crisis?

With 80% of trials missing enrollment targets, expect sponsors to push decentralised, site-light designs that shift screening and consent work onto your clinic.

Oncology · Fierce Biotech · 17 Sept

Kennedy appoints 8 new US Preventive Services Task Force members

USPSTF grades drive US screening and preventive coverage, so a reconstituted panel may shift recommendations Indian clinicians often follow.

General Medicine · Fierce Healthcare · 17 Sept

Cardiometabolic Risk Factors, Obesity Phenotypes, and Novel Anthropometric Indices in Patients With Acute Coronary Syndrome: A Hospital-Based Case-Control Study in Central India

BMI was not associated with ACS (Exp(B) 1.208, 95% CI 0.816-1.790, p=0.345). WHtR was (Exp(B) 2.473, 95% CI 1.638-3.732). MUO versus MHNW: OR 3.33, 95% CI 1.10-10.12.

Cardiology · Cureus · 17 Sept

Occupational Pesticide Exposure and Risk of Non-melanoma Skin Cancer Among U.S. Adults: A Systematic Review

When taking a skin history in outdoor or agricultural workers, ask about pesticide exposure alongside UV, since it may add independent NMSC risk.

Oncology · Cureus · 17 Sept

Acute Psychosis and Dissociative Syndrome Following Binge Recreational Nitrous Oxide Use: A Case Report

She had disorientation, delusions and hallucinations requiring involuntary admission; homocysteine was 25.2 µmol/L with vitamin B12 270 pg/mL, both normalising on B12 and folate. Risperidone caused neutropenia, resolving on aripiprazole.

Psychiatry · Cureus · 17 Sept

Suspected Bulbar-Predominant Myasthenia Gravis Exacerbation in an Older Adult With Respiratory Deterioration and Silent Aspiration: A Case Report

Videofluoroscopy showed significant silent aspiration of thin and mildly thickened liquids; serial blood gases showed persistent hypercapnia with preserved pH and markedly elevated bicarbonate. Respiratory status stabilized on IVIG and steroids, but bulbar dysfunction and dysphagia persisted.

Neurology · Cureus · 17 Sept

De-escalating Therapy in Obstructive Sleep Apnoea After Glucagon-Like Peptide-1 Receptor Agonist-Induced Weight Loss: A Narrative Review

Patients losing weight on GLP-1s may no longer need CPAP, so plan repeat sleep studies and structured de-escalation rather than leaving them on fixed therapy.

General Medicine · Cureus · 17 Sept

Duodenal Ulcer Perforation Following Tirzepatide Injections for Weight Loss Management: A Case Report

Localised retroperitoneal perforation of a duodenal ulcer in the third duodenal portion, two weeks after dose escalation; managed conservatively with antibiotics, proton pump inhibitor and bowel rest, and discharged improved.

Gastroenterology · Cureus · 17 Sept

Fibroma of the Testis and Epididymis: A Case Report on a Testis-Sparing Management Approach

Benign paratesticular fibromas can mimic malignancy; normal markers and well-circumscribed imaging should prompt testis-sparing excision rather than orchiectomy in young men.

Urology · Cureus · 17 Sept

Purpureocillium lilacinum Fungemia Masquerading as an Unidentified Yeast in a Heavily Immunosuppressed Patient With Relapsed Multiple Myeloma and Therapy-Related Mixed-Phenotype Acute Leukemia: A Case Report

Blood culture grew a yeast-like organism unidentified by rapid multiplex PCR; reference mycology identified P. lilacinum about two weeks later. Susceptibility showed amphotericin B resistance and high itraconazole MIC, with lower MICs to posaconazole and voriconazole.

Oncology · Cureus · 17 Sept

Renal Cyst Rupture Mimicking Grade V Renal Trauma After Blunt Injury: A Case Report Highlighting the Risk of Radiologic Overstaging

Contrast-enhanced CT showed apparent grade V renal injury with parenchymal lacerations, large perirenal hematoma and active contrast extravasation, plus bilateral renal and hepatic cysts; he stayed hemodynamically stable and was managed conservatively with no progression.

Urology · Cureus · 17 Sept

Efficacy and Safety of Etomidate Versus Ketamine for Endotracheal Intubation in Critically Ill Patients: A Systematic Review and Meta-Analysis

Pooled data show no clear hemodynamic or safety winner between etomidate and ketamine, so agent choice can follow your unit's protocol and the individual patient's shock state.

Anaesthesiology · Cureus · 17 Sept

Rare EGFR mutation increases lung cancer risk 62 times in never smokers

A germline EGFR variant confers far higher lung cancer risk than smoking in never-smokers, so family history may soon justify screening decisions beyond tobacco exposure.

Oncology · Fierce Biotech · 17 Sept

Ultrasonic-With-Ballistic Versus Pneumatic Lithotripsy in Percutaneous Nephrolithotomy for 2-4 cm Renal Calculi: A Prospective Quasi-experimental Comparative Study in a Bangladeshi Tertiary-Care Hospital

Stone-free rate 96.2% versus 73.1% (risk difference 23.1%, 95% CI 3.0% to 42.5%). Disintegration time 22.1 versus 28.9 minutes; operative time 57.7 versus 86.2 minutes. Complications and hospital stay did not differ.

Urology · Cureus · 17 Sept

Clinical Experience With a High-Definition Three-Dimensional Exoscope for Spinal Surgery: A Review of 30 Consecutive Initial Cases

All 30 procedures were completed with the exoscope without switching to another visualisation device. No patient had postoperative worsening of the JOA score and no exoscope-related surgical complications occurred.

Orthopaedics · Cureus · 17 Sept

Hospitals push back as FDA flags high markups on hospital consumables

Fixed markups on consumables could change what your hospital charges for devices and supplies, so watch how this pricing framework is finalised.

General Medicine · ETHealthworld · 17 Sept

An Atypical Presentation of Richter's Transformation in Chronic Lymphocytic Leukemia: Stroke-Like Onset With Multiorgan Involvement Including the Heart and Seminal Vesicles

In CLL patients with sudden stroke-like deficits or unexplained cardiac or genitourinary masses, consider Richter's transformation rather than assuming a vascular or primary cause.

Oncology · Cureus · 17 Sept

Comparative Evaluation of Three Endodontic File Systems for Pericervical Dentin Preservation and Canal Transportation Using Cone-Beam Computed Tomography: An In Vivo Study

File system choice measurably changes how much pericervical dentin you sacrifice and how much the canal transports, affecting fracture risk in your root-treated teeth.

Medicine · Cureus · 17 Sept

India had largest number of people exposed to 30 days of risky heat from Jun-Aug: Analysis

Expect more heat exhaustion, dehydration and cardiac events this summer; counsel at-risk patients on hydration, timing of outdoor work and medication adjustments.

General Medicine · ETHealthworld · 17 Sept

Intravascular Ultrasound-Guided Iliofemoral Venous Stenting: In-Stent Mural Thrombus as a Possible Early Sign of Occult Malignancy

In-stent mural thrombus after iliofemoral venous stenting may signal undiagnosed cancer, so consider malignancy workup when it appears on surveillance imaging.

Cardiology · Cureus · 17 Sept

Diagnostic Accuracy of Preoperative Magnetic Resonance Imaging for Staging Endometrial Carcinoma: A Retrospective Single-Centre Study

MRI correctly determined myometrial invasion depth in 62.5% and overall stage in 53.1%. Upstaging occurred in 21.9%, downstaging in 25%. For myometrial invasion: sensitivity 58.3%, specificity 65.0%, PPV 50.0%, NPV 72.2%.

Obstetrics & Gynaecology · Cureus · 17 Sept

Oura, Counsel Health join CMS ACCESS model to test whether wearables and AI can improve chronic care at scale

If CMS pays for AI-guided remote monitoring in cardio-kidney-metabolic disease, your chronic-care workflow may shift to wearable-driven data between visits.

Cardiology · Fierce Healthcare · 17 Sept

Feasibility and Safety of Intraoperative Abdominal Warming During Spinal Surgery in the Prone Position: A Pilot Study

Median core temperature rose from 36.5 °C at induction to 37.0 °C at end of surgery. Two patients had transient hypothermia below 36.0 °C, both recovering within 90 minutes. No skin complications.

Anaesthesiology · Cureus · 17 Sept

Longeveron’s phase 2b stem cell flop spurs cost cutting, exploration of ‘all options’

A phase 2b mesenchymal stem cell trial in hypoplastic left heart syndrome missed its endpoint, so don't expect this cell therapy to reach your paediatric cardiac patients soon.

Cardiology · Fierce Biotech · 17 Sept