Archive

Povidone-Iodine Versus Homemade Salt/Soda Mouthwash for the Prophylaxis of Radiation-Induced Oral Mucositis in Head and Neck Cancer: A Quasi-experimental Study

If a cheap salt-and-soda rinse matches povidone-iodine, you can spare head-and-neck radiotherapy patients the cost and iodine exposure during treatment.

Oncology · Cureus · 19 Sept

Beyond Iron Supplementation: A Narrative Review of the Structural Determinants of Anaemia in Pregnancy in India

Iron deficiency accounts for only about half of anaemia cases; capillary and venous haemoglobin estimates differ substantially; haemoglobin testing was removed from NFHS-6

Obstetrics & Gynaecology · Cureus · 19 Sept

New Statin-Safety Reassurance: How Far Can It Extend to South Asian Patients?

Statin safety data from Western cohorts may not transfer to South Asian patients, whose differing pharmacokinetics could alter myopathy and intolerance risk at standard doses.

Cardiology · Cureus · 19 Sept

Beyond Antibiotics: Bacteriophage Therapy Against Multidrug-Resistant Pathogens in the Era of Antimicrobial Resistance

Up to 80% of chronic infections involve biofilms that shield bacteria from antibiotics; phages can penetrate and disperse these structures and can resensitise resistant bacteria to previously ineffective drugs

General Medicine · Cureus · 19 Sept

A Hidden Catastrophe: Ruptured Abdominal Aortic Aneurysm Presenting as Acute Ischemic Stroke

In stroke-code patients, check for abdominal pain and leg mottling before thrombolysis; a ruptured AAA can masquerade as stroke and anticoagulation would be fatal.

General Surgery · Cureus · 19 Sept

Minimally Invasive Coronary Artery Bypass Grafting for Predominantly Multivessel Coronary Artery Disease: Early Perioperative Outcomes of 149 Patients

Adds single-centre evidence that multivessel MICS-CABG avoids sternotomy with acceptable early outcomes, though results remain confined to high-volume specialised centres.

Cardiology · Cureus · 19 Sept

Regenerative Medicine in the Management of Musculoskeletal Pain: Mechanisms, Clinical Applications, and Future Directions

No pooled effect estimate reported. Review concludes effectiveness, safety and feasibility vary substantially by modality, indication, product standardisation and study quality, with knowledge gaps remaining

Orthopaedics · Cureus · 19 Sept

Thirty-Day Outcomes in Ultrasound Versus CT-Only Imaging in Obese Adults With Acute Appendicitis

No significant difference in emergency room revisits: 11.98% with ultrasound versus 13.64% with CT only (RR = 0.879, p = 0.44). Abscess, perforation and peritonitis also showed no difference.

Radiology · Cureus · 19 Sept

Efficacy, Tolerability, and Safety of Fluoxetine for Panic Disorder in Adults: A Review

Fluoxetine remains a first-line SSRI for panic disorder; this review consolidates its response rates and side-effect profile to guide dosing and patient counselling.

Psychiatry · Cureus · 19 Sept

A Review of Guidelines for the Use of Tranexamic Acid in the Management of Postpartum Hemorrhage and Assessment of Associated Maternal Outcomes

No new patient data. The review reports that guidelines differ on timing and placement of tranexamic acid within postpartum haemorrhage treatment algorithms.

Obstetrics & Gynaecology · Cureus · 19 Sept

Researchers find genetic answer to lung cancer in those who never smoked

A rare inherited EGFR variant raised lung cancer risk 25-fold in never-smokers, so consider germline testing in non-smoking patients with lung cancer and their families.

Oncology · ETHealthworld · 19 Sept

Patient-Reported Outcomes Following Two-Tined Three-Site Conventional Radiofrequency Ablation of Genicular Nerves for Chronic Knee Pain

Average NRS reduction was -3.17 at 0-3 months (p<0.0001), -1.31 at 3-6 months (p<0.05), and -1.92 at 6-12 months (p<0.05). Half maintained relief for 11.17 months (95% CI: 7.29, 13.40).

Anaesthesiology · Cureus · 19 Sept

Extraocularly Manipulated Flangeless Intrascleral Haptic Fixation of Intraocular Lens Using Zigzag Needles

Mean BCVA improved from 0.56 ± 0.66 to 0.15 ± 0.40 logMAR. ECD fell from 2243 ± 319 to 1999 ± 502 cells/mm². Mean IOL tilt 5.74 ± 2.95 degrees; complications 5.6% per event.

Ophthalmology · Cureus · 19 Sept

Efficacy and Safety of Vitex Extract on Menopausal Symptoms and Quality of Life in Postmenopausal Women: A Randomized Placebo-Controlled Trial

Adds randomized evidence that a well-tolerated botanical may reduce vasomotor symptoms, giving an option for women who decline or cannot take hormone therapy.

Obstetrics & Gynaecology · Cureus · 19 Sept

Potential Use of AI Chatbots by Patients With Bowel Tumors: Opportunities and Implications for Low- and Middle-Income Countries

Patient-facing tools supported feasibility, acceptability, symptom reporting and communication; accuracy for screening, diagnosis and treatment advice varied by task and was less reliable in complex cases.

Oncology · Cureus · 19 Sept

Iatrogenic Pseudoaneurysm After Arthroscopic Knee Procedures: A Systematic Review of Presenting Features, Injured Vessels, Management, and Outcomes

Post-arthroscopy swelling that persists or pulses may be a pseudoaneurysm, not a hematoma; suspect it before attributing symptoms to DVT or infection.

Orthopaedics · Cureus · 19 Sept

Multimodal Opioid-Sparing Analgesia for Lumbar Decompression in a Patient With Opioid-Associated Sphincter of Oddi Symptoms: A Case Report

In patients with prior opioid-induced sphincter of Oddi pain, a multimodal opioid-sparing regimen can cover lumbar decompression without triggering recurrent biliary-type symptoms.

Anaesthesiology · Cureus · 19 Sept

Patient-Reported Outcomes After Septoplasty With Bilateral Radiofrequency Inferior Turbinate Reduction: A Prospective Cohort Study

Confirms combined septoplasty and radiofrequency turbinate reduction improves patient-reported nasal obstruction and quality of life, supporting the combined procedure in symptomatic septal deviation with turbinate hypertrophy.

General Surgery · Cureus · 18 Sept

CMS restores $12B in frozen supplemental Medicaid funds

Restored payments to safety-net hospitals protect staffing and services that many of your Medicaid patients depend on.

Medicine · Fierce Healthcare · 18 Sept

Post-acne Erythema: A Systematic Review of Randomized Controlled Trials on the Comparative Efficacy and Safety of Interventions Across Clinical, Instrumental, and Patient-Reported Outcomes

No intervention has proven standard for post-acne erythema; this review maps which randomized options actually reduce redness so you can counsel patients realistically.

General Medicine · Cureus · 18 Sept

Unmasking Brugada Syndrome With Oral Propafenone in a Resource-Limited Setting: A Case Report

Oral propafenone can unmask type 1 Brugada patterns where IV ajmaline or flecainide is unavailable, letting you confirm the diagnosis before a fatal arrhythmia does.

Cardiology · Cureus · 18 Sept

Postextubation Stridor: An Analysis of Incidence, Risk Factors, and Clinical Outcomes in Mechanically Ventilated Patients

22 of 651 (3.4%) developed PES; 36.4% (8/22) were reintubated; 30-day and 60-day mortality were both 0%. Female sex was independently associated (OR 3.65; 95% CI 1.49-9.47).

Anaesthesiology · Cureus · 18 Sept

Assessment of Preoperative Serum Vitamin D Levels in Differentiated Thyroid Cancer

If low preoperative vitamin D tracks with differentiated thyroid cancer, it is a cheap, already-ordered test that could flag patients needing closer thyroid evaluation.

Oncology · Cureus · 18 Sept

Artelo’s ex-AstraZeneca cannabinoid agonist holds its own against GLP-1 drug semaglutide in obese mice

A preclinical oral cannabinoid agonist matched semaglutide for weight loss in mice, but human data are years away and clinicians should not expect a near-term alternative.

Endocrinology · Fierce Biotech · 18 Sept

FSSAI takes legal action against Nestle India over sub-standard infant formula

Two Nestle infant formulas face regulatory action over HMO and whey protein claims, so verify what you tell parents about these products' composition.

Paediatrics · ETHealthworld · 18 Sept

Pulsed Low-Dose-Rate Radiotherapy (PLDR): A Comprehensive Review of Radiobiological Rationale and Clinical Applications in Modern Cancer Care

PLDR lets you re-irradiate previously treated fields with less normal-tissue toxicity, useful when reirradiation is the only local option left.

Oncology · Cureus · 18 Sept

Impact of Short-Term Fluoride Supplementation in Pregnancy on the Maternal Microbiome, Pregnancy, and Neonatal Outcomes: A Pilot Randomized Controlled Trial

No differences in vaginal microbiome richness or diversity between groups. Oral taxa differences were nominal and unadjusted for multiple testing. Clinical outcomes showed no consistent pattern; the trial was not powered for efficacy or safety.

Obstetrics & Gynaecology · Cureus · 18 Sept

Clinical and Patient-Reported Outcomes in Non-English-Speaking Patients Undergoing Primary Total Knee Arthroplasty

Language barriers may worsen short-term TKA outcomes independent of ethnicity, so arrange interpreters and translated rehab instructions for non-English-speaking patients.

Orthopaedics · Cureus · 18 Sept

Does That Thumb Trigger Finger Release Have You Feeling “Nerve”-ous?

Radial and ulnar digital nerves cross the thumb flexion crease at variable positions, so blind percutaneous release risks transection; know the anatomy before cutting.

Orthopaedics · Cureus · 18 Sept

Intrabiliary Rupture of a Hepatic Hydatid Cyst Causing Mechanical Biliary Obstruction: A Case Report of Endoscopic Management With a Self-Expandable Metal Stent

In endemic hydatid regions, endoscopic SEMS placement can decompress cyst-related biliary obstruction without surgery, though stent-related cholangitis and long-term patency need follow-up.

Gastroenterology · Cureus · 18 Sept

Salvage Management of Anterior-Posterior Compression (APC) Type II Pelvic Ring Injury Using Isolated Posterior Fixation After Anterior Implant Removal: A Case Report

When anterior pelvic implants fail or infect, isolated posterior fixation can still salvage an APC-II ring, sparing your patient a redo anterior approach.

Orthopaedics · Cureus · 18 Sept

With pioneering ADHD data, Alkermes eyes orexin agonist as potential ‘company changer’

If orexin agonists work in ADHD, a new non-stimulant mechanism may eventually reach patients who cannot tolerate or misuse current stimulants.

Psychiatry · Fierce Biotech · 18 Sept

Discordance Between Gated Single-Photon Emission Computed Tomography Myocardial Perfusion Imaging and Coronary Angiography in Dilated Cardiomyopathy

In DCM, SPECT-MPI and angiography can disagree on ischaemic versus non-ischaemic aetiology, so don't let a perfusion report alone decide whether a patient needs revascularisation workup.

Cardiology · Cureus · 18 Sept

DPHARM: Where to begin with AI in clinical trials?

AI is entering trial recruitment and monitoring first, so expect AI-screened referrals and algorithm-flagged safety signals in studies your patients join.

Medicine · Fierce Biotech · 18 Sept

Assessing the Influence of Propofol Sedation Versus Propofol-Free Sedation on Recovery From Sepsis and Septic Shock in Mechanically Ventilated ICU Patients: A Retrospective, Propensity-Score Matched, Cohort Study

Median ICU-free days were similar: 6.3 (2.1-14.7) non-propofol versus 6.8 (3.3-13.3) propofol, p=0.303. Before matching, mortality was higher without propofol (43.3% vs 32.3%, p=0.031); after matching, no significant difference.

Anaesthesiology · Cureus · 18 Sept

Clotting Beyond Boundaries: Extensive Iliocaval Thrombosis Revealing Homozygous Factor V Leiden Mutation in a Young Adult Following Prolonged Air Travel

In a young patient with extensive thrombosis after long-haul travel, test for inherited thrombophilia such as homozygous factor V Leiden, not just provoked VTE.

General Medicine · Cureus · 18 Sept

Refreshed Novo corrals 3 new early-stage obesity drugs from Kallyope

Three early-stage obesity candidates entering Novo's pipeline signal more oral or combination options may reach your patients within a few years.

Endocrinology · Fierce Biotech · 18 Sept

Op-ed: Health AI is moving fast. America needs rules that keep up

A patchwork of US state AI rules could delay the clinical tools you will soon be asked to trust; watch for a single national standard instead.

Medicine · Fierce Healthcare · 18 Sept

Medtronic earns FDA clearance for LigaSure use with its Hugo robotic system

Adds a robotic vessel-sealing option to a system already used in India, widening instrument choice for minimally invasive surgery.

General Surgery · Fierce Biotech · 18 Sept

Incidence and Progression of Acute Kidney Injury Following Head and Neck Surgeries for COVID-19-Associated Mucormycosis: A Prospective Observational Study

AKI developed in 9 of 49 patients (18.4%). Pre-existing hypertension was more prevalent in AKI patients (77.8% vs 32.5%; p = 0.02), and baseline eGFR was lower (87.4 ± 27.1 vs 102.9 ± 17.4 mL/min/1.73 m²; p = 0.03).

Anaesthesiology · Cureus · 18 Sept