Archive

When Steroids Backfire: Tinea Incognito Following Treatment for Presumed Psoriasis

Steroid-treated plaques that worsen or lose their annular edge should prompt a KOH mount before you escalate immunosuppression.

General Medicine · Cureus · 22 Sept

Rapid Improvement of Persistent Catatonia Temporally Associated With Amantadine After Benzodiazepine Intolerance and Discontinuation of Electroconvulsive Therapy: A Case Report

When lorazepam is poorly tolerated and ECT cannot continue, amantadine may offer a rapid alternative for persistent catatonia, though this is a single case.

Psychiatry · Cureus · 22 Sept

Early Post-transcatheter Aortic Valve Implantation (TAVI) Haemodynamics With SAPIEN Balloon-Expandable and Evolut Self-Expanding Valve Platforms: A Retrospective Single-Centre Cohort Study

Valve choice at TAVI affects early gradients, so knowing how SAPIEN and Evolut differ helps you anticipate haemodynamics and follow-up echo findings.

Cardiology · Cureus · 22 Sept

Late-Onset Prosthetic Valve Dysfunction Associated With Hypoattenuated Leaflet Thickening Detected After a New Heart Murmur: A Case Report

A new murmur after sutureless bioprosthetic AVR may signal HALT; consider CT to detect leaflet thickening before overt valve failure develops.

Cardiology · Cureus · 22 Sept

Missed Early Signs of Tuberculosis in Pregnancy: Insights From a Case Series of Disseminated Life-Threatening Maternal Disease and Adverse Fetal Outcomes

All five had life-threatening disease: three of five had extensive pulmonary TB needing ventilatory support; one had tubercular meningitis with hydrocephalus; one had tubercular peritonitis with pyoperitoneum. Fetal outcomes included growth restriction, prematurity, demise, and congenital TB.

Obstetrics & Gynaecology · Cureus · 22 Sept

Vitamin D Supplementation in Granulomatous Disease: Why Individualized Assessment May Be Safer Than Universal Thresholds

No new data. Low 25(OH)D can occur with preserved or raised 1,25(OH)2D, so supplementing on 25(OH)D alone may cause hypercalcaemia or hypercalciuria.

General Medicine · Cureus · 22 Sept

Treatment-Resistant Psychosis in an Adolescent at Risk of Metabolic Syndrome: A Case Report

When metabolic risk rules out clozapine and other antipsychotics in a psychotic adolescent, you need a documented pathway through the remaining options.

Psychiatry · Cureus · 21 Sept

Pharmacokinetic, Pharmacodynamic, and Clinical Outcomes of Vancomycin and β-Lactam Antibiotics in Adults With Augmented Renal Clearance: A Systematic Review

Vancomycin troughs were below 10 µg/mL in more than 60% of ARC patients; AUC/MIC above 400 mg·h/L was reached in 82.14% with once-every-eight-hours dosing versus 46.42% with once-every-twelve-hours dosing.

General Medicine · Cureus · 21 Sept

Mini-Laparotomy Enterolithotomy for Gallstone Ileus in an Elderly Patient: A Case Report

In elderly patients with recurrent cholecystitis presenting as bowel obstruction, consider gallstone ileus and treat with enterolithotomy rather than a more extensive biliary procedure.

General Surgery · Cureus · 21 Sept

Central Centrifugal Cicatricial Alopecia in Black Women: Diagnostic Challenges and Molecular Insights

No pooled effect estimates reported. Dermoscopy and histopathology remain key to diagnosis, with follicular dropout, perifollicular fibrosis and lymphocytic inflammation; PADI3 and PPAR-gamma pathways are implicated but of uncertain clinical significance.

Medicine · Cureus · 21 Sept

Levamisole-Adulterated Cocaine-Associated Vasculopathy in a 73-Year-Old Woman: Diagnostic Challenges in Primary Care

In cocaine users with retiform purpura and atypical ANCA, suspect levamisole adulterant rather than primary vasculitis — misdiagnosis leads to unnecessary immunosuppression.

General Medicine · Cureus · 21 Sept

Medical groups, city of Columbus sue to challenge final Medicaid work requirements rule

If you see Medicaid patients, work-reporting rules from January could strip coverage unless courts block them, disrupting chronic-disease care.

General Medicine · Fierce Healthcare · 21 Sept

Democratic senators reintroduce bill outlining stiffer cybersecurity standards, $1.3B hospital implementation assistance

If passed, it would fund hospital cybersecurity upgrades and enforce standards, reducing the ransomware risk that can shut down your records and imaging mid-shift.

Medicine · Fierce Healthcare · 21 Sept

Artificial Intelligence and Anatomical Variation: A Narrative Review of Detection, Classification, and Educational Applications

Direct clinical evidence concentrated in dental and cranio-maxillofacial imaging; performance was task-, dataset- and prevalence-dependent, and external validation, calibration and transparent handling of correlated observations were uncommon.

Radiology · Cureus · 21 Sept

Clinical Profile and Outcomes of Children With Congenital Heart Disease Undergoing Surgery at a Tertiary Care Cardiac Center in Central Gujarat and Their Anthropometric Profiles During Follow-Up: A Prospective Longitudinal Observational Study

Baseline growth and surgical outcome data from non-metropolitan India help you counsel families on expected catch-up growth after CHD repair.

Paediatrics · Cureus · 21 Sept

Aetna expands bundled prior auths for cancer care

If your Medicaid cancer patients are Aetna-insured, one bundled auth now covers a whole regimen instead of separate approvals per drug and scan.

Oncology · Fierce Healthcare · 21 Sept

Alzheimer’s cases in India could be up to 5 times higher than reported number: Experts

Dementia is likely far more common than clinic figures suggest, so screen cognitively in older patients rather than waiting for memory complaints.

Neurology · ETHealthworld · 21 Sept

Maternal Bivalent Respiratory Syncytial Virus Prefusion F (RSVpreF) Vaccination in Panama: A Retrospective Follow-Up Study

Any reaction reported by 55.5% (95% CI 48.6%-62.2%), mostly injection-site pain (48.0%); fever 2.5%. Preterm birth 2.0%, low birth weight 2.5%, neonatal jaundice 20.0%.

Obstetrics & Gynaecology · Cureus · 21 Sept

Beyond the Hospital: Spatial Inequality and Structural Divergence in Stroke Mortality Across the United States (2020-2024)

Largest relative increases in medium (+8.4%) and large fringe metros (+7.3%); home deaths surged in 2021 (n=41,423); out-of-hospital Gini=0.5321 versus in-hospital Gini=0.5045.

Neurology · Cureus · 21 Sept

Cell-Type-Specific Transcriptomic Alterations in the Epileptic Prefrontal Cortex and Complementary Neuroimaging Findings in an Independent Cohort

Maps which prefrontal cell types are transcriptionally altered in epilepsy and links them to imaging changes, pointing toward cell-specific targets rather than seizure-focus-only models.

Neurology · Cureus · 21 Sept

FDA Updates Regulations to Advance Innovative Alternatives to Animal Testing

Non-animal safety testing may speed first-in-human entry for new drugs you prescribe or trial, though clinical evidence standards are unchanged.

Medicine · FDA — Press Announcements · 21 Sept

Terminologia Anatomica Compliance in Generative Artificial Intelligence Outputs: A Structured Narrative Review and Terminology-Specific Verification Checklist

Image studies consistently found omissions, invented structures, incorrect relationships and mislabeled anatomy; one citation study found substantial reference hallucination and limited PubMed identifier accuracy

Medicine · Cureus · 21 Sept

Rapid Pain Reduction and Wound Closure Following Treatment With an Amorphous Silica-Based Fiber Wound Matrix in Partial-Thickness Thermal Burns: A Case Report

In this single case, a silica-based fiber matrix relieved refractory 6-10/10 burn pain and achieved closure after standard dressings and analgesia failed.

General Surgery · Cureus · 21 Sept

Thyroid Ectopia in the Euthyroid Patient: A Rare Case Discussion

A midline base-of-tongue mass in a euthyroid patient may be ectopic thyroid, not carcinoma; imaging alone cannot distinguish them, so biopsy before resection.

General Surgery · Cureus · 21 Sept

Evaluation of Pre-analytical Errors in the Histopathology Laboratory at a Tertiary Care Hospital in Kenya

Most histopathology errors happen before the specimen reaches the lab, so tightening collection, labelling and fixation in your own theatre and clinic is where diagnostic quality is won.

Medicine · Cureus · 21 Sept

Chronic Complications Following Dengue Infection: A Scoping Review

Dengue is no longer only an acute illness — ask about persistent fatigue, hepatic and neurological symptoms weeks after recovery, especially in endemic states.

General Medicine · Cureus · 21 Sept

Govt nod for Biovigilance Programme, IPC to monitor adverse events linked to organ transplants

Transplant centres will now report adverse events and reactions to a national IPC programme, so expect new reporting duties and clearer safety signals for your post-transplant patients.

General Surgery · ETHealthworld · 21 Sept

White House plans to put NIH grants under political control: reports

Political review of NIH grants could slow or block funding for trials and studies that shape the evidence behind your clinical decisions.

Medicine · Fierce Healthcare · 21 Sept

Bilateral Staghorn Calculi With Stent Encrustation in a Patient With an Ileal Conduit Requiring Staged Endourological Procedures: A Case Report

Bilateral staghorn calculi, stent encrustation and a conduit calculus were cleared completely using staged percutaneous and transconduit endoscopic techniques, with significant improvement in renal function.

Urology · Cureus · 21 Sept

Bioactivity and Regenerative Potential of Calcium Silicate-Based Endodontic Sealers on Human Periodontal Ligament Stem Cells: A Systematic Review of In Vitro Cellular Mechanisms

Calcium silicate sealers generally maintained or increased metabolic activity while AH Plus showed lower activity; 12 scratch-wound studies showed migration comparable to or greater than controls, and 11 Alizarin Red S studies showed increased mineral deposition.

Medicine · Cureus · 21 Sept

Seroprevalence and Temporal Trends of Syphilis Among Blood Donors at Dhiraj Blood Bank in Waghodia, Gujarat, India: A Retrospective Study

111 (1.49%) samples were VDRL-reactive; 45 (40.5%) of these were confirmed by Syphi Microlisa ELISA, giving an overall seroprevalence of 0.60%. Annual rates were 0.85% in 2023, 0.08% in 2024, and 0.90% in 2025.

General Medicine · Cureus · 21 Sept

Imaging Correlation of Color Doppler Ultrasound, CT Angiography, and MR Angiography Findings in Extracranial Carotid and Vertebral Artery Disease Among Ischemic Stroke Patients: A Prospective Observational Study

Doppler agrees well enough with CTA/MRA for first-line carotid and vertebral stenosis workup, so you can triage stroke patients without immediate advanced angiography.

Neurology · Cureus · 21 Sept

Esophageal Carcinoma Incidence and Survival Analysis: A Population-Based Cancer Registry Study in Central India

Median survival 178.33 days; 1-, 3-, 5-, 10-year OS 31.3%, 19.7%, 17.4%, 14.6%. Median survival 232 days localized vs 68 days distant disease. Chemoradiotherapy HR 0.48, surgery plus chemotherapy HR 0.45.

Oncology · Cureus · 21 Sept

Literature Review of Occult Hepatitis B Infection and Hepatitis B Core Antibody-Positive Blood Donors

Anti-HBc-positive donors with occult HBV can transmit infection where only HBsAg or NAT is used, so know your blood bank's screening algorithm before transfusing.

Gastroenterology · Cureus · 21 Sept

Spontaneous Perigastric Hematoma and Hemoperitoneum Associated With Rivaroxaban Therapy: A Case Report and Review of the Literature

Perigastric hematoma measured 96 mm × 58 mm with hemoperitoneum; hemoglobin fell from 14.8 g/dL to 12.3 g/dL. No active contrast extravasation. Rivaroxaban was stopped and he recovered fully without transfusion or procedure.

Gastroenterology · Cureus · 21 Sept

Prevalence and Pattern of Hemoglobinopathies Among Women of Reproductive Age Attending a Tertiary Care Center in Central Uttar Pradesh: A Prospective Observational Study

Regional prevalence data support offering hemoglobinopathy carrier screening and reproductive counselling to women of reproductive age in Central Uttar Pradesh.

Obstetrics & Gynaecology · Cureus · 21 Sept

Rice-Grain Calcifications: A Classic Sign of Muscular Cysticercosis

Radiographs showed numerous rice-grain calcifications parallel to muscle fibers, consistent with known cysticercosis; myalgia was not attributable to these lesions and resolved within one week with paracetamol alone

General Medicine · Cureus · 21 Sept

Ectopic Ureteral Orifice: An Unusual Cause of Urinary Incontinence in an Adult

CT urography showed a left duplex collecting system with an ectopic ureter draining the upper renal pole into the vagina. Ureterovesical reimplantation (Politano-Leadbetter) gave immediate, complete continence.

Urology · Cureus · 21 Sept

Centre calls for review of Hospital Consumable Prices after Mundhe flags MRP gaps: Sources

If margins on consumables are capped, your hospital's device procurement costs and billing to patients could shift, so watch for pricing changes.

Medicine · ETHealthworld · 21 Sept

Prevalence of Deep Vein Thrombosis in Patients With Cervical Cancer

Baseline and on-treatment DVT screening in cervical cancer patients may catch silent thrombosis before it becomes life-threatening.

Oncology · Cureus · 21 Sept