Archive

STAT+: What health tech leaders are talking about in Washington policy circles

US health-AI policy signals shape which clinical AI tools reach Indian practice, so knowing the direction helps you judge vendor claims.

Medicine · STAT News — Health Tech · 30 Sept

Serious and Non-serious Hepatitis Reports in the U.S. Vaccine Adverse Event Reporting System, 1990–2026: A Cross-Sectional Analysis

VAERS reports cannot establish causation, so reassure patients that reported post-vaccination hepatitis does not mean vaccines cause hepatitis; report suspected cases regardless.

Gastroenterology · Cureus · 30 Sept

Persistent Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) Syndrome Associated With Vancomycin-Impregnated Orthopedic Cement: A Case Report

If a patient develops DRESS after vancomycin cement, removing systemic vancomycin alone won't resolve it — the cement itself must be revised.

Orthopaedics · Cureus · 30 Sept

Reoperation and Complication Rates Following Percutaneous Bone Graft and Headless Screw Fixation for Scaphoid Non-union: A 10-Year, Single-Centre Experience

Ten-year single-centre data on union and reoperation rates after percutaneous grafting and headless screw fixation help you counsel patients on expected revision risk.

Orthopaedics · Cureus · 30 Sept

Electrical Alternans as an Early Clue to a Rapidly Evolving Large Pericardial Effusion: The Role of Point-of-Care Ultrasound

Electrical alternans on ECG after pericarditis should prompt immediate bedside ultrasound, since tamponade can develop within days of a normal echocardiogram.

Cardiology · Cureus · 30 Sept

Functional Outcomes of Midshaft Clavicle Fractures Treated With Plate Osteosynthesis: A Prospective Observational Study

Supports plating displaced midshaft clavicle fractures in adults to reduce non-union and restore shoulder function, rather than relying on conservative treatment alone.

Orthopaedics · Cureus · 30 Sept

Standalone Middle Meningeal Artery Embolization Versus Surgical Evacuation for Nontraumatic Subdural Hematoma: A Propensity-Matched Multicenter Real-World Study

Propensity-matched real-world data suggest standalone MMA embolization may rival surgical evacuation in nontraumatic subdural hematoma, supporting a less invasive option in frail or recurrent cases.

Neurology · Cureus · 30 Sept

Hospital stocks fall as SC questions drug mark-ups

If the court mandates cost-plus drug billing, your hospital's pharmacy margins and patient billing practices will need restructuring.

General Medicine · ETHealthworld · 30 Sept

Procalcitonin and Presepsin in Gram-Negative Sepsis: Diagnostic, Prognostic, and Antimicrobial Stewardship Perspectives

PCT and presepsin may flag Gram-negative sepsis earlier and guide antibiotic de-escalation, but neither reliably replaces cultures for choosing therapy.

General Medicine · Cureus · 30 Sept

Pandoraea Species Bacteremia in a Neonate: A Case Report

Rare nonfermenters like Pandoraea are misread as Burkholderia, so in a septic neonate with no standard breakpoints, request identification beyond routine panels before choosing therapy.

Paediatrics · Cureus · 30 Sept

Patient-Reported Concerns and Factors Associated With Anesthetic Preference: A Cross-Sectional Study on Why Patients Choose General Over Regional Anesthesia

Patients decline regional anesthesia largely from fear and misinformation, so preoperative counselling should directly address their stated concerns rather than assume clinical benefit persuades them.

Anaesthesiology · Cureus · 30 Sept

Timing of Growth Hormone Therapy Initiation and Final Adult Height in Idiopathic Short Stature: A Systematic Review

Largest registry analysis of 3,939 prepubertal children found no significant mean gain in near-adult height SDS in the ISS subgroup; late-pubertal cohorts reported final heights of 170.9-173.5 cm in males.

Endocrinology · Cureus · 30 Sept

Management Patterns and Outcomes of Ogilvie Syndrome in the Absence of Standardized Protocols: A Single-Center Case Series From Puerto Rico

Without standardized protocols, ACPO management varies widely; this series shows what outcomes look like when neostigmine and decompression decisions are ad hoc.

Gastroenterology · Cureus · 30 Sept

CSIR-CCMB study describes how viral infection may pave way for Parkinson's disease

Adds viral infection to the differential for Parkinson's risk, suggesting post-encephalitic patients may warrant closer neurological follow-up.

Neurology · ETHealthworld · 30 Sept

Adrenocortical Carcinoma: A Case Report on the Diagnostic and Therapeutic Approach

Uncontrolled hypertension can be the presenting sign of adrenocortical carcinoma; this case shows the imaging and surgical workup, though adjuvant therapy remains unstandardised.

Oncology · Cureus · 30 Sept

Evaluating the Clinical Impact of an Enhanced Recovery After Surgery (ERAS) Program: A Quality Improvement and Practice Change Study at Al-hada Armed Forces Hospital

Structured ERAS protocols cut length of stay and complications, but only if audit and multidisciplinary buy-in are built in from the start.

General Surgery · Cureus · 30 Sept

Pilot Mixed-Methods Evaluation of Simulation-Based Focused Cardiac Ultrasound Teaching for Final-Year Medical Students

Mean confidence was 9.86/15 post-session versus 3.67/15 pre-session (median 10 vs 4; U = 0.0, P < 0.001). Mean knowledge was 4.71/5 versus 4.22/5, with high baseline scores.

Cardiology · Cureus · 30 Sept

Anterior Uveitis in Patients With Methylenetetrahydrofolate Reductase (MTHFR) Gene Polymorphisms: A Case Series

In young women with recurrent unilateral anterior uveitis and no systemic cause, MTHFR testing may reveal a thrombotic contributor worth considering before labelling it idiopathic.

Ophthalmology · Cureus · 30 Sept

Health-Related Quality of Life in Patients With Fibrosing Interstitial Lung Diseases: A Study Using the King’s Brief Interstitial Lung Disease (K-BILD) Questionnaire

K-BILD scores track how breathlessness and cough erode daily life in fibrosing ILD, giving you a validated patient-reported measure beyond spirometry for clinic follow-up.

General Medicine · Cureus · 30 Sept

Multimodal Large Language Models Rate Wetlab Suturing Repeatably but Fail to Detect Training-Related Improvement: A Pilot Study With Expert Assessment

AI scoring of suturing videos is repeatable but misses real improvement, so it cannot yet replace faculty assessment of trainees' progress.

General Surgery · Cureus · 30 Sept

Pityriasis Lichenoides Chronica: A Diagnostic and Therapeutic Challenge

PLC mimics eczema and psoriasis but needs biopsy and staged therapy; recognising the spectrum avoids years of misdiagnosed topical steroid use.

General Medicine · Cureus · 30 Sept

An Evolving Clinical Phenotype Preceding the Diagnosis of Eosinophilic Granulomatosis With Polyangiitis: A Case Report

In adults with late-onset asthma and rising eosinophils, consider EGPA before the vasculitic phase, since the full syndrome may take months to declare itself.

General Medicine · Cureus · 30 Sept

Baseline Optical Coherence Tomography Features and Visual Outcomes After Anti-vascular Endothelial Growth Factor Therapy for Retinal Vein Occlusion-Associated Macular Edema: A Prospective Observational Study

Baseline OCT features may predict which RVO patients gain vision after three anti-VEGF injections, helping you counsel on expected recovery and follow-up intensity.

Ophthalmology · Cureus · 30 Sept

Guideline Concordance of Antibiotic Recommendations From Large Language Models in Dentistry: A Vignette-Based Evaluation in Georgian and English

LLM antibiotic advice for dental infections diverges from guidelines and varies by language, so verify any AI-suggested prescription before you sign it.

Medicine · Cureus · 30 Sept

Preserving Muscle Health During Weight Loss: Evidence Across Lifestyle, Surgical, and Pharmacological Interventions

Caloric restriction reduced weight and fat mass but caused variable fat-free mass loss; greater energy restriction sometimes meant greater lean loss. Higher protein plus resistance exercise best preserved lean tissue. Lean mass loss did not necessarily impair strength or function.

Endocrinology · Cureus · 30 Sept

Intra-aortic Balloon Counterpulsation-Assisted Cardiac Support in the Anesthetic Management of Surgery for Acute Cervical Spine Compression With Severe Coronary Artery Disease in the Prone Position

Intra-aortic balloon counterpulsation was inserted after induction of general anesthesia and maintained intraoperative hemodynamics; no outcome measures or follow-up data are reported.

Anaesthesiology · Cureus · 30 Sept

Postoperative Day 1 Mean Arterial Pressure and 30-Day Mortality or Day 7 Renal Replacement Therapy After Ventricular Assist Device Implantation

POD 1 MAP after VAD implantation may track with 30-day death or day-7 RRT, so early haemodynamic targets could affect renal and survival outcomes.

Cardiology · Cureus · 30 Sept

8 weeks versus 12 weeks of sofosbuvir-velpatasvir for treatment-naive, non-cirrhotic, chronic hepatitis C (RESOLVE): a multicentre, open-label, non-inferiority, randomised controlled trial in India.

If 8 weeks of sofosbuvir-velpatasvir matches 12 weeks in non-cirrhotic HCV, you can cut treatment duration and cost by a third for these patients.

Gastroenterology · Lancet · 30 Sept

Early national comparison of robotic versus conventional knee replacements for arthritis using National Joint Registry data: target trial emulation study.

Registry data on 697,145 knees show whether robotic TKR/UKR improves early revision and complication rates before you commit your unit to the platform.

Orthopaedics · BMJ · 30 Sept

Innate immune sensing of Plasmodium sporozoite cell traversal drives protective T cell responses.

Explains how attenuated sporozoite malaria vaccines trigger innate sensing, informing which candidates may produce durable T cell protection in endemic settings.

General Medicine · Nature microbiology · 30 Sept

Intravenous hyaluronidase-expressing oncolytic adenovirus with chemotherapy in metastatic pancreatic cancer: a randomized phase 2b trial.

If adding IV VCN-01 to gemcitabine-nab-paclitaxel improves survival in metastatic PDAC, it would be the first oncolytic virus regimen to enter first-line practice.

Oncology · Nature Medicine · 30 Sept

Early national comparison of robotic versus conventional hip replacements for arthritis using National Joint Registry data: target trial emulation study.

Registry data on 666,283 hip replacements show whether robotic THR improves early outcomes enough to justify its cost and operating time.

Orthopaedics · BMJ · 30 Sept

Cardiovascular safety of orforglipron versus insulin glargine in adults with type 2 diabetes at increased cardiovascular risk (ACHIEVE-4): a phase 3, event-driven, randomised, open-label, non-inferiority, active comparator trial.

Offers an oral GLP-1 option for type 2 diabetes patients at cardiovascular risk, though it only matches insulin glargine rather than reducing events.

Endocrinology · Lancet · 30 Sept

Histologic Features and Clinical Outcomes of Lean Metabolic Dysfunction-Associated Steatotic Liver Disease.

Lean patients with MASLD still carry real fibrosis risk, so don't withhold elastography or referral just because BMI is normal.

Gastroenterology · JAMA · 30 Sept

Host cell traversal by Plasmodium parasites drives sterilizing T cell-mediated immunity following immunization.

Explains why whole-sporozoite malaria vaccines induce sterile protection, guiding which vaccine platforms may eventually reach travellers and endemic-region patients.

General Medicine · Nature microbiology · 30 Sept

Accelerated Versus Standard Ponseti Method for Idiopathic Clubfoot: A Prospective Comparative Study of Correction and Outcomes

Biweekly Ponseti casting may halve treatment time in idiopathic clubfoot without losing correction, easing the burden on families travelling for weekly casts.

Orthopaedics · Cureus · 30 Sept

Mechanistic Differences in Adult-Onset and Juvenile-Onset Huntington’s Disease and the Potential Role of Neurodevelopment

Juvenile-onset Huntington's may reflect disrupted circuit maturation rather than pure degeneration, which could mean different timing and targets for intervention in younger patients.

Neurology · Cureus · 30 Sept

Primary Cutaneous Diffuse Large B-cell Lymphoma, Leg Type, With Rapid Systemic Progression in an Elderly Patient: A Case Report

Leg-type cutaneous DLBCL can disseminate within weeks, so biopsy leg nodules promptly and stage systemically rather than treating as indolent skin disease.

Oncology · Cureus · 30 Sept

Medical Applications of Graph Convolutional Networks Using Electronic Health Records: A Scoping Review

GCNs model relationships across EHR data to sharpen diagnosis and risk prediction, but this review finds most models remain unvalidated in real clinical workflows.

General Medicine · Cureus · 30 Sept

FDA Investigation Leads to Charges Against Two Indian Nationals Involved in Transnational Counterfeit Drug Distribution Scheme

Counterfeit medicines reaching Indian patients through online and grey channels are a real prescribing risk; verify sourcing and warn patients against unregulated purchases.

General Medicine · FDA — Press Announcements · 30 Sept