Archive

Predictors of Postoperative Neurological Outcome After Surgical Evacuation of Traumatic Acute Subdural Hematoma: A Retrospective Cohort Study

Unfavorable outcome occurred in 74 (61.7%) and mortality was 21.7% (26/120). Independent predictors included GCS ≤8 (aOR 4.86), bilateral non-reactive pupils (aOR 4.10), and hypotension (aOR 2.79).

Neurology · Cureus · 30 Sept

Management of Patients Undergoing Chemotherapy in Conservative Dentistry

Before dental work in a patient on chemotherapy, check for mucositis, bleeding risk and xerostomia, and time invasive procedures to the post-nadir window.

Oncology · Cureus · 30 Sept

Magnetic Resonance Imaging Evaluation of Azygos Vein Deviation and Risk of Pedicle Screw Penetration in Thoracic Adolescent Idiopathic Scoliosis

Preoperative MRI mapping of the azygos vein at T7-T10 may flag which thoracic pedicle screws risk vascular injury in AIS correction.

Orthopaedics · Cureus · 30 Sept

Hospital Indicators for the Management of Native and Prosthetic Valve Infective Endocarditis Across Brazilian Regions From 2015 to 2024

Native-valve: 13,920 admissions, 1,966 deaths (14.1 per 100). Prosthetic-valve: 6,610 admissions, 1,115 deaths (16.9 per 100). Death rates per 100,000 rose significantly in the Southeast and South for native-valve disease.

Cardiology · Cureus · 30 Sept

Factors Associated with Emergency Department Revisit and Urologic Intervention Following Discharge of Renal Colic Patients: A Retrospective Cohort Study from a Military Hospital in the Kingdom of Bahrain

Identifies which discharged renal colic patients are likely to return or need intervention within 14 days, helping you target follow-up and safety-net advice.

Urology · Cureus · 30 Sept

Thrombophlebitis in an Adolescent Patient With Primary Carnitine Deficiency: A Case Report

In adolescents with primary carnitine deficiency on oral L-carnitine, consider thrombophlebitis when venous inflammation appears, as supplementation may not fully prevent this complication.

Paediatrics · Cureus · 29 Sept

Digital Glide Path© for Fibre Post Retrieval Through Guided Endodontics in a Patient With Factor VIII Deficiency

Guided endodontics allowed safe fibre-post retrieval in a haemophilia patient, avoiding the bleeding risk that makes conventional retreatment hazardous in coagulopathy.

Medicine · Cureus · 29 Sept

Cochlear Implants Versus Hearing Aids in Children With Auditory Neuropathy Spectrum Disorder: A Systematic Review

In children with auditory neuropathy, cochlear implants may outperform hearing aids when amplification fails, so early audiology referral and candidacy assessment matter for language outcomes.

Paediatrics · Cureus · 29 Sept

Pre-emptive Circulatory Support Before Emergency Tracheal Intubation: A Systematic Review

Evidence remains too uncertain to routinely justify pre-emptive vasopressors or fluids before emergency intubation; individualise to the haemodynamically fragile patient.

Anaesthesiology · Cureus · 29 Sept

Waltz Health, Fresenius Kabi partner for direct-to-payer biosimilar program

Direct-to-payer biosimilar channels could cut acquisition costs for infliximab and trastuzumab, but Indian clinicians should watch whether supply and pharmacovigilance keep pace.

Medicine · Fierce Healthcare · 29 Sept

Delayed Recognition of Autism Spectrum Disorder and Off-Label Lurasidone After Intolerance to Risperidone and Aripiprazole in a Latin American Child: A Case Report

ASD and OCD diagnosed about 27 months after presentation. Low-dose lurasidone 20 mg nightly gave sustained improvement over one year; hallucinations resolved within about three months, with no significant adverse effects.

Psychiatry · Cureus · 29 Sept

Recurrent Facial Miliaria Crystallina Revealing Underlying Hyperthyroidism: A Report of Two Cases

Recurrent facial miliaria without heat or fever triggers should prompt thyroid function testing, as both reported cases had underlying hyperthyroidism.

Endocrinology · Cureus · 29 Sept

Ex-Genentech, Meta, AWS AI leaders launch health AI lab with $500M backing

A $500M full-stack health AI platform could eventually supply clinical decision tools and infrastructure your hospital buys, but nothing is deployable yet.

Medicine · Fierce Healthcare · 29 Sept

'This is carnage', says SC on markup of 10 times on cancer drugs by hospitals

If hospitals must let patients buy chemo drugs outside, your patients could pay a fraction of in-house prices — expect pressure to change dispensing practice.

Oncology · ETHealthworld · 29 Sept

Iatrogenic Cushing Syndrome With Glucocorticoid-Induced Adrenal Insufficiency Following Prolonged Topical Clobetasol Use in an Adolescent

Morning cortisol <30 nmol/L, ACTH <5 ng/L; Synacthen cortisol <30 nmol/L at baseline and 30 minutes, 38 nmol/L at 60 minutes. Adrenal reserve recovered by seven months after stopping clobetasol.

Endocrinology · Cureus · 29 Sept

Chronic Myeloid Leukemia Progressing to Early T-Cell Precursor Lymphoblastic Blast Phase Following Treatment Default: An Integrated Morphologic, Immunophenotypic, Cytogenetic, and Molecular Case Report

Treatment interruption in chronic-phase CML can drive rare T-cell lymphoblastic blast crisis, so reinforce adherence and re-biopsy any patient losing molecular response.

Oncology · Cureus · 29 Sept

Treatment-Induced Neuropathy Presenting as Thoracic Radiculopathy and Abdominal Wall Protrusion After Marked Glycemic Improvement With Tirzepatide

HbA1c fell from 11.0% to 6.6% over seven months with 17-pound weight loss; weeks later he developed severe thoracoabdominal neuropathic pain and abdominal wall weakness.

Endocrinology · Cureus · 29 Sept

Carotid Cavernous Fistula: A Case Report of a Rare Diagnosis and Presentation

Periorbital swelling that fails to settle should prompt you to consider CCF, since missing it risks vision loss from a treatable arteriovenous shunt.

Ophthalmology · Cureus · 29 Sept

STAT+: Anthropic joins ARPA-H clinical AI moonshot, will hold closed-door health care event

Anthropic is joining a US federal push to build clinical AI tools, signalling the models likely to reach Indian EHRs and triage workflows next.

Medicine · STAT News — Health Tech · 29 Sept

Atypical Multisegmental Involvement in Suspected Ischemic Colitis: A Case Report

WBC 22.2 K/µL with lactate 0.8 mmol/L; CT showed multisegmental colitis and colonoscopy showed noncontiguous inflammation of rectum, sigmoid, hepatic flexure, ascending colon and cecum with normal terminal ileum

Gastroenterology · Cureus · 29 Sept

A Care-Level-Stratified Algorithm for Neuromodulation in Persistent Spinal Pain Syndrome Type 2: Critical Appraisal of Contemporary Evidence Adapted to Latin American Health Systems

Offers a tiered pathway for post-laminectomy pain, helping you decide when to escalate from medical therapy to spinal cord stimulation in resource-limited settings.

Neurology · Cureus · 29 Sept

Physician Knowledge, Attitudes, and Practices Regarding Viral Exanthem Diagnosis and Mandatory Reporting Requirements in Major Metropolitan Regions of Florida, USA

Most clinicians miss mandatory reporting steps for measles and rubella; knowing your local reporting pathway matters more as outbreaks return.

General Medicine · Cureus · 29 Sept

Factors Associated With Uncontrolled Blood Pressure and Its Association With Cardiovascular and All-Cause Mortality Among Adults Receiving Antihypertensive Therapy: A Retrospective Cohort Study Using NHANES 2013-2018 Linked Mortality Data

Uncontrolled BP affected 56.9%. Higher odds in other Hispanic (AOR 1.50, 95% CI 1.08-2.07), non-Hispanic Black (AOR 1.63, 95% CI 1.29-2.05) and non-Hispanic Asian adults (AOR 1.68, 95% CI 1.15-2.45). No significant mortality association.

Cardiology · Cureus · 29 Sept

Severe Hypercapnia and Hemodynamic Instability During Carbon Dioxide Insufflation During Robot-Assisted Thoracic Surgery

During robot-assisted thoracic surgery, CO2 capnothorax can drive severe hypercapnia and haemodynamic instability, so watch end-tidal CO2 and blood pressure trends, not just the surgical field.

Anaesthesiology · Cureus · 29 Sept

Pentalogy of Cantrell: Sonographic Findings and Toyama Classification

Omphalocele, ectopia cordis, inferior sternal defect and ventricular septal defect seen; anterior diaphragmatic and pericardial deficiency suspected but not confirmed. Pregnancy terminated before genetic testing.

Obstetrics & Gynaecology · Cureus · 29 Sept

Subependymal Giant Cell Astrocytoma Mimicking Recurrent Ependymoma: Imaging Clues to the Diagnosis of Tuberous Sclerosis Complex

In a child with prior ependymoma, a new intraventricular mass may be TSC-related SEGA, not recurrence; imaging clues can spare unnecessary reoperation.

Neurology · Cureus · 29 Sept

Heidi launches AI agents to automate clinical administrative tasks

If it works, it could cut the after-hours documentation and paperwork that keeps you at the desk long after clinic ends.

Medicine · Fierce Healthcare · 29 Sept

Blue Toe Syndrome and Acute Kidney Injury Following Transcatheter Aortic Valve Replacement: A Biopsy-Proven Case of Cholesterol Embolization Syndrome

Creatinine rose from baseline 1.2-1.5 mg/dL to 4.24 mg/dL about 2.5 months post-TAVR; biopsy showed cholesterol clefts in intrarenal arteries. Creatinine improved to approximately 3.1 mg/dL by discharge.

Cardiology · Cureus · 29 Sept

Molecular and Conventional Tests in Onychomycosis: A Systematic Review of Paired Diagnostic Discordance and Clinical Interpretation

PCR and culture disagree often in onychomycosis, so a negative culture alone should not rule out fungal nail infection before starting or stopping treatment.

General Medicine · Cureus · 29 Sept

Immune Background Profiles Across B-cell Lymphoproliferative Disorders

Background T- and NK-cell patterns on routine flow cytometry may help subtype B-CLPDs without extra testing, but this is descriptive data, not a validated diagnostic rule.

Oncology · Cureus · 29 Sept

Clinical and Dermoscopic Evaluation of Patients With Disorders of Hypopigmentation and Depigmentation

Dermoscopy can distinguish vitiligo from pityriasis alba and other hypopigmentary mimics at the bedside, reducing unnecessary biopsies and referrals.

Medicine · Cureus · 29 Sept

Acute-on-Chronic Limb Ischemia Mimicking Cellulitis: A Diagnostic Pitfall

Erythema and swelling in a vasculopath can be critical limb ischemia, not cellulitis; check pulses and perfusion before committing to antibiotics alone.

General Surgery · Cureus · 29 Sept

Local Corticosteroid Injection in Hand Surgery: A Review of Molecular Mechanisms, Steroid Selection, and Clinical Outcomes

Evidence strongest for stenosing flexor tenosynovitis, de Quervain tenosynovitis and mild-to-moderate carpal tunnel syndrome; limited or context-dependent for thumb carpometacarpal arthritis, Dupuytren nodules and ganglion cysts.

Orthopaedics · Cureus · 29 Sept

Impact of Morphine on Early Recovery After Anterior Cruciate Ligament Reconstruction: A Case-Control Study

Day 0 VAS 5.6 ± 2.7 vs 5.3 ± 2.7 (p = 0.0339); night pain 68.2% vs 61.3% (p = 0.0202); day 1 5.2 ± 2.4 vs 4.8 ± 2.4 (p = 0.0014). Differences did not exceed MCID.

Orthopaedics · Cureus · 29 Sept

Severe Rhabdomyolysis and Acute Kidney Injury Following Rosuvastatin Reinitiation During Ticagrelor Therapy: A Case Report and Literature Review

CK and creatinine rose markedly with anuria and dark-red urine; creatinine reached 6.3 mg/dL, BUN 82 mg/dL, bicarbonate 15 mmol/L. Hemodialysis was required; creatinine fell to 1.3 mg/dL by week three.

Cardiology · Cureus · 29 Sept

Ultrasound-Guided Vascular Access Training: A Single-Center Experience Using Gelatin-Based Simulation Models

97% reported increased confidence with the gelatin model and 91% found volunteer-based ultrasound practice beneficial; the main barriers were limited ultrasound machine access and insufficient training time.

Anaesthesiology · Cureus · 29 Sept

Loop-Mediated Isothermal Amplification as an Alternative to Conventional Smear Microscopy in Pulmonary Tuberculosis

Against the composite reference standard, TB-LAMP showed sensitivity 74.36% and specificity 91.80%, and identified cases missed by conventional techniques.

General Medicine · Cureus · 29 Sept

STAT+: The last ‘breakthrough’ devices to get special treatment from Medicare

If you implant FDA-designated breakthrough devices, the add-on Medicare payment pathway is closing, which may change which devices hospitals are willing to buy.

Medicine · STAT News — Health Tech · 29 Sept

Does Reconstructive Surgery Improve Psychological Recovery After Burn Injury?

Reconstruction may restore function without resolving depression or PTSD, so screen burn survivors psychologically rather than assuming surgery alone fixes recovery.

General Surgery · Cureus · 29 Sept

H1N1 dominates flu strains in India, accounts for 3 out of 4 cases: WHO

With H1N1 causing three of four flu cases, test and treat influenza early in febrile patients rather than presuming dengue or COVID.

General Medicine · ETHealthworld · 29 Sept