Archive

Zodoc acquires health tech company Sohar Health for automated benefits eligibility checks

Automated eligibility checks at booking could cut the front-desk insurance verification work and surprise billing that delays your patients' appointments.

Medicine · Fierce Healthcare · 13d

Mental health patients report year-long waits to access care: Amaha Report

Only 11.3% of 13,825 respondents reached care within a month, so expect patients presenting late and severely; ask about delay at first consult.

Psychiatry · ETHealthworld · 13d

STAT+: Lobbyists and trade groups fight to shape how states regulate medical AI

State rules being drafted now will decide who is accountable when AI tools you use misread a scan or suggest a dose.

Medicine · STAT News — Health Tech · 13d

Confido Health nabs $12.5M to scale agentic AI across PE-backed medical groups

If your group is PE-backed, this funds AI agents handling scheduling, intake and billing workflows, so expect vendor pitches and pressure to automate front-office staff.

Medicine · Fierce Healthcare · 14d

Bat-borne zoonoses: transmission, impact, prevention, and management.

Nipah and rabies outbreaks in India mean early recognition of bat exposure and timely post-exposure prophylaxis remain the mainstay you can act on.

General Medicine · BMJ · 14d

Intraoperative Dobutamine Plus Norepinephrine to Prevent Postoperative Acute Kidney Injury in Septic Shock: A Randomized Clinical Trial.

Adding intraoperative dobutamine to norepinephrine in septic shock surgery may reduce postoperative AKI; check the effect size before changing your intraoperative vasopressor regimen.

Anaesthesiology · JAMA · 14d

Continuous Glucose Monitoring in Non-Insulin-Treated Type 2 Diabetes.

CGM improved glycaemic control in non-insulin-treated type 2 diabetes managed in primary care, supporting wider use beyond insulin-treated patients.

Endocrinology · NEJM · 14d

Reframing cancer therapy through tumor plasticity.

Explains why tumours regress then relapse off targeted therapy: drug-tolerant states are reversible, so rechallenge or plasticity-directed combinations may work where dose escalation fails.

Oncology · Nature cancer · 14d

Fluid Therapy in Mechanically Ventilated Critically Ill Adult Patients.

Documents how widely fluid dosing and choice vary worldwide in ventilated ICU patients, giving you a benchmark to audit your own unit's practice against.

Anaesthesiology · JAMA · 14d

Intermittent or Continuous Renal-Replacement Therapy in Acute Kidney Injury.

Intermittent hemodialysis was noninferior to continuous therapy in critically ill AKI, so ICU teams can choose intermittent dialysis when continuous circuits are unavailable.

General Medicine · NEJM · 14d

Effect of Vasopressin Initiation Threshold on Septic Shock Mortality: The VASSPR Cluster Crossover Randomized Strategy Trial.

A hospital-level strategy of starting vasopressin earlier rather than later in septic shock may change your unit's second-line vasopressor protocol.

General Medicine · JAMA · 14d

Evaluation of the accuracy, completeness, and compliance of current summary reporting of adverse events to the Food and Drug Administration using the manufacturer and user facility device experience (MAUDE) database: cross sectional study.

Device adverse-event summaries you rely on for safety signals are often incomplete and non-compliant, so underreporting may hide risks in devices you implant.

Medicine · BMJ · 14d

Isoflurane-Based Inhaled Sedation in Mechanically Ventilated Adults With Acute Hypoxemic Respiratory Failure: The SAVE-ICU Randomized Clinical Trial.

If inhaled isoflurane sedation lowers mortality in acute hypoxemic respiratory failure, ICU sedation protocols should shift from propofol and midazolam toward volatile agents.

Anaesthesiology · JAMA · 14d

Talazoparib plus enzalutamide in high-volume metastatic hormone-naive prostate cancer: a randomized phase 2 trial.

PSA <0.2 ng/ml at 12 months was 73% (95% CI 56-86%) with the combination versus 64.7% (95% CI 38-86%) with enzalutamide alone; grade ≥3 adverse events were 68% versus 35%, mainly anemia (41%).

Oncology · Nature Medicine · 14d

Personalized neoantigen-targeting cancer vaccines in ovarian cancer: a phase 1 trial.

Nine of 12 evaluable Cohort B patients were vaccinated (75%, 90% CI 47-93%) and 1 of 9 Cohort A patients (11%, 90% CI 0.6-43%). No unexpected safety signals; no discontinuations for toxicity.

Oncology · Nature Medicine · 14d

CVS, DOJ reach $315M settlement in opioid prescription case

Signals tighter scrutiny of opioid dispensing; expect stricter prescription verification and documentation expectations when your patients fill controlled substances.

General Medicine · Fierce Healthcare · 14d

Probably Genetic raises $12M to scale rare disease dataset, support drug discovery

A physician-ordered test for undiagnosed rare disease could shorten the years-long diagnostic odyssey your patients currently endure.

General Medicine · Fierce Healthcare · 14d

Measles update: US passes 4,000 cases, Pennsylvania reports sixth death

Falling vaccination coverage is driving measles resurgence with deaths; check and catch up MMR status in unvaccinated children and adults at every visit.

Paediatrics · Fierce Healthcare · 14d

STAT+: Takeaways from an evaluation of Google’s diagnostic chatbot, AMIE

AMIE's Lancet evaluation shows how an AI chatbot performs on real diagnostic reasoning, a preview of tools that may soon triage patients before you see them.

General Medicine · STAT News — Health Tech · 14d

Early-onset Alzheimer's disease looks very different to late-onset version: Study

In younger patients with depression, dizziness or head injury, keep early-onset Alzheimer's on the differential — the comorbidity pattern differs from late-onset disease.

Neurology · ETHealthworld · 14d

Karnataka FDA orders hospitals to disclose base price of medicines, med devices on bills

Your hospital bills must now show acquisition cost alongside MRP for drugs and devices, so audit your billing systems and vendor margins before compliance checks begin.

Medicine · ETHealthworld · 13 Oct

Reporting completeness of clinical trials evaluating large language model interventions in medicine: systematic review.

Before trusting any LLM tool in your clinic, know that trials of these tools routinely under-report methods and outcomes, so published results may not be reproducible.

General Medicine · BMJ · 13 Oct

A multiview video-text model detects obstructive coronary stenosis and predicts 1-year cardiovascular events from angiography.

A model reading whole angiographic runs, not single frames, could standardise stenosis calls and flag patients heading for a 1-year event.

Cardiology · Nature cardiovascular research · 13 Oct

Delirium.

Delirium is common and preventable; review how to spot at-risk patients on sedatives or anticholinergics and cut their risk.

General Medicine · Annals · 13 Oct

Benzodiazepine Use Early in Pregnancy and Risk for Congenital Malformations.

Adjusted absolute risk for any malformation was 4.0% versus 4.1% (Medicaid) and 4.9% versus 4.8% (MarketScan); pooled adjusted RR 0.99 (95% CI, 0.96 to 1.03).

Obstetrics & Gynaecology · Annals · 13 Oct

Human-artificial intelligence collaboration for comanaging epilepsy in real time.

Seizure detectors improved precision from patient feedback alone, without expert intervention, in a pseudoprospective simulation; the platform processed sleep, medication, cognition and seizure probability biomarkers.

Neurology · Nature Medicine · 13 Oct

How Would You Screen This 26-Year-Old Woman for Cervical Cancer? Grand Rounds Discussion From Beth Israel Deaconess Medical Center.

Half of all cervical cancers occur in women underscreened or never screened; HPV is associated with nearly all cases, though most infections are transient.

Obstetrics & Gynaecology · Annals · 13 Oct

Follow-up Outcomes of 100 Children with Frequently Relapsing and Steroid Dependent Nephrotic Syndrome Treated with Oral Cyclophosphamide: A Retrospective Cohort Study.

Response rate was 67%, with median relapse-free interval 9.1 months. At median follow-up 72.5 months, 28% achieved sustained remission and 69% had infrequent relapses; 56% needed another steroid-sparing agent.

Paediatrics · Indian pediatrics · 13 Oct

Johns Hopkins Medicine taps OpenEvidence to bring AI into medical education, clinical care

Signals that AI answer engines are entering mainstream academic clinical workflows, so expect such tools in your hospital's decision support sooner than later.

General Medicine · Fierce Healthcare · 13 Oct

Suki secures $90M in series E funding to accelerate growth, expand AI capabilities

Suki's voice AI drafts clinical notes inside EHRs; this funding signals the ambient-documentation tools vying for your clinic are consolidating and scaling.

General Medicine · Fierce Healthcare · 12 Oct

The Survival Gap: Why India’s Breast Cancer Survival Trails the World

Late presentation and patchy screening drive India's below-median breast cancer survival, so opportunistic palpation and prompt referral in your clinic still outperform any new drug.

Oncology · ETHealthworld · 12 Oct

Centre asks states to ensure hospitals display service rates

Your hospital must now publicly display service charges, so audit your rate boards and billing counters before state compliance reviews begin.

General Medicine · ETHealthworld · 12 Oct

Google unveils new Fitbit Edge tracker as tech giant expands health monitoring ambitions

Consumer wearables feeding AI-derived health signals may bring patients to you with alerts of unclear validity, so know what these devices claim to detect.

General Medicine · Fierce Healthcare · 12 Oct

Obesity tops global health threats by avoidable burden: Lancet Commission

Obesity now outranks other modifiable risks in avoidable DALYs, so weight management deserves the same clinical priority as hypertension and smoking cessation in your practice.

Endocrinology · ETHealthworld · 12 Oct

Population-scale reconstruction of menopause dynamics reveals a physiological cliff at the final menstrual period.

Menopause is not a gradual decline: biomarkers shift sharply at the final menstrual period, so timing hormone and cardiovascular counselling around that date, not symptoms alone.

Obstetrics & Gynaecology · Nature Medicine · 12 Oct

Development and Validation of an Adult Medical Urgency Score for US Donor Heart Allocation.

US-CRS had higher time-dependent AUC than the 6-status system (mean 0.807 vs 0.693). In match-run analysis (n=45 530 donor hearts), 67% of recipients moved down in rank order and first-candidate 6-week mortality rose from 11.2% to 15.7%.

Cardiology · JAMA · 12 Oct

Heart Transplant for Advanced Heart Failure: A Review.

Contemporary post-transplant survival is 91.5% at 1 year and 80.3% at 5 years; each additional 'I NEED HELP' criterion raised death or hospitalisation risk (adjusted HR 1.19, 95% CI 1.11-1.27).

Cardiology · JAMA · 12 Oct

A health-system-scale, episode-resolved multimodal atlas of cancer cachexia.

Cachectic episodes clustered near disease progression and were associated with inferior outcomes in nearly all cancer types; a multivariate model predicted impending cachectic weight loss in lung, colorectal and prostate cancer.

Oncology · Nature Medicine · 12 Oct

Doctors find new scan better at detecting ovarian cancer spread

Better detection of peritoneal spread could change which advanced ovarian cancer patients you refer for surgery rather than upfront chemotherapy.

Obstetrics & Gynaecology · ETHealthworld · 11 Oct

Strengthening health systems to prioritise, provide care, and prevent osteoarthritis: a roadmap for global health policy.

No new trial data. By 2050 almost 1 billion people are expected to live with osteoarthritis; about 600 million already do. Three priorities: surveillance and policy embedding, scaled person-centred care, and prevention targeting excess bodyweight and joint injury.

Orthopaedics · Lancet · 11 Oct