Archive

Hospitals push back as FDA flags high markups on hospital consumables

Fixed markups on consumables could change what your hospital charges for devices and supplies, so watch how this pricing framework is finalised.

General Medicine · ETHealthworld · 17 Sept

India had largest number of people exposed to 30 days of risky heat from Jun-Aug: Analysis

Expect more heat exhaustion, dehydration and cardiac events this summer; counsel at-risk patients on hydration, timing of outdoor work and medication adjustments.

General Medicine · ETHealthworld · 17 Sept

Chimeric Antigen Receptor T-cell (CAR-T) Therapy in Autoimmune Diseases: A Narrative Review

CAR-T is moving beyond oncology into refractory SLE, systemic sclerosis and vasculitis, so expect referrals for cell therapy in patients who have failed standard immunosuppression.

General Medicine · Cureus · 17 Sept

Sentara Health pilots GW RhythmX's AI precision care platform to support emerging primary care models

If AI risk stratification at the point of primary care proves out, it could change how chronic disease is triaged before specialists ever see the patient.

General Medicine · Fierce Healthcare · 17 Sept

Zileuton Beyond Asthma: A Multifaceted 5-Lipoxygenase Inhibitor With Emerging Therapeutic Potential Across Inflammation, Cancer, Neuroprotection, and Fibrosis

Zileuton's upstream 5-LOX blockade is being explored beyond asthma in cancer, fibrosis and neuroprotection, but evidence is still preclinical or early — not yet a reason to change prescribing.

General Medicine · Cureus · 16 Sept

Theory of Artificial Intelligence Adaptation for Linguistic Concordance: Bridging Gaps in Patient-Centered Communication

AI translation could let you counsel patients in their own language, but this is theory only — no accuracy or safety data yet for clinical use.

General Medicine · Cureus · 16 Sept

Relapsing Polychondritis With Severe Airway Involvement Mimicking Refractory Asthma: A Diagnostic Challenge

Fixed airflow obstruction with minimal bronchodilator reversibility, inspiratory stridor, and progressive tracheobronchial thickening sparing the posterior membranous wall; symptoms persisted despite high-dose corticosteroids and cyclophosphamide.

General Medicine · Cureus · 16 Sept

The Bidirectional Relationship Between Rheumatoid Arthritis and Periodontitis: Current Evidence and Clinical Implications

No pooled effect estimates are reported. Evidence suggests periodontal infection amplifies systemic inflammation and autoimmune responses, while RA accelerates periodontal breakdown; periodontal therapy may improve selected RA activity measures, but consistency and clinical significance remain uncertain.

General Medicine · Cureus · 16 Sept

Sex-specific biological aging clocks across organs and omics.

Female and male clocks diverged markedly; sex-specific clocks predicted systemic disease and all-cause mortality in sex- and organ-dependent patterns, and brain clock tracked cognitive decline in preclinical AD

General Medicine · Nature Medicine · 16 Sept

Prolonged Primary Cytomegalovirus Infection in an Immunocompetent Adult Successfully Treated With Valganciclovir

Fever and liver dysfunction persisted despite supportive care; after valganciclovir, she became afebrile within five days and laboratory abnormalities improved.

General Medicine · Cureus · 16 Sept

Delays, tech failures abound in CMS' WISeR AI prior auth pilot, documents show

If AI prior auth spreads to India, expect the same delays and denials; document your appeals now.

General Medicine · Fierce Healthcare · 15 Sept

STAT+: Medicare to expand its pilot that pays for technology to manage chronic diseases

Expanded Medicare coverage of remote monitoring signals a coming reimbursement pathway for chronic-disease tech, worth watching if you run diabetes or hypertension clinics.

General Medicine · STAT News — Health Tech · 15 Sept

STAT+: New documents reveal problems with Medicare’s prior-authorization pilot

If AI-driven prior authorization spreads, expect more denials and appeals paperwork for your Medicare patients' imaging, procedures and referrals.

General Medicine · STAT News — Health Tech · 15 Sept

Phenotypic Characterization of Multidrug-Resistant Pseudomonas aeruginosa Isolated From Patients With Ventilator-Associated Pneumonia: Insights Into Resistance Mechanisms and Biofilm Formation

Complete resistance to piperacillin and imipenem (100% each), piperacillin-tazobactam and meropenem 98.08% each; aztreonam most susceptible (83.65%). MBL production in 80 (76.92%), ESBL in 7 (6.73%). Biofilm in 54 (51.92%) by tube method.

General Medicine · Cureus · 15 Sept

STAT+: Medicare’s AI prior authorization pilot was rushed and full of problems, new documents reveal

If AI-driven prior authorization spreads, expect more denials and delays for your Medicare patients; document necessity carefully and appeal with clinical detail.

General Medicine · STAT News — Health Tech · 15 Sept

Virological and metabolic outcomes after switching to dolutegravir or rilpivirine in virologically suppressed adults with HIV in Thailand: an open-label, randomised, controlled, non-inferiority trial.

In suppressed patients on efavirenz, switching to dolutegravir or rilpivirine kept viral suppression but differed in weight and metabolic effects, informing which switch suits whom.

General Medicine · Lancet regional health. Southeast Asia · 15 Sept

Broadly neutralizing antibodies in adult males living with HIV undergoing analytical treatment interruption: secondary and exploratory outcomes of the phase II randomized controlled RIO trial.

Rebounding virus showed significant selection for resistance to 10-1074-LS but not 3BNC117-LS. Greater baseline reservoir sensitivity to autologous antibodies and 10-1074 correlated with longer time to rebound.

General Medicine · Nature Medicine · 15 Sept

Evaluation and Management of Anemia in Chronic Kidney Disease: Synopsis of the Kidney Disease: Improving Global Outcomes 2026 Clinical Practice Guideline.

Eight graded recommendations: iron guided by transferrin saturation and ferritin, intravenous iron preferred over oral in hemodialysis, correctable causes addressed first, ESA preferred over HIF-PHI first-line, upper Hb target below 11.5 g/dL.

General Medicine · Annals · 15 Sept

Cryo-EM structures of Candida albicans chitin synthase Chs1 reveal a druggable translocation channel.

DA binds the chitin translocation channel, occluding polymer extrusion, and shows potent synergy with nikkomycin Z against C. albicans and C. auris.

General Medicine · Nature microbiology · 15 Sept

On-premise medical AI agents for reliable clinical decision-making.

Accuracy was 90.04% on the seven-disease task and 83.8% on the four-disease task. Diagnostic behavioural consistency best predicted correctness (AUC 0.860; 0.875 under stress testing). At threshold 0.90, 49.4% of cases retained at 98.9% accuracy.

General Medicine · Nature Medicine · 15 Sept

Bias Mitigation Across the Healthcare Artificial Intelligence Lifecycle: A Structured Narrative Review

No primary quantitative result; the review catalogues sampling, adversarial learning, subpopulation techniques, and new model structures, and proposes a lifecycle protocol spanning data acquisition to deployment

General Medicine · Cureus · 14 Sept

Potential new TB vaccines could save millions of lives: Gavi

If new TB vaccines reach India's immunisation schedule, they could cut a disease you still diagnose weekly in young adults and children.

General Medicine · ETHealthworld · 14 Sept

States are betting millions on remote monitoring. Providers, tech groups say proposed Medicare policy could undercut it

If Medicare cuts remote monitoring reimbursement, the RPM programmes your rural patients depend on may lose funding, so check whether your service is exposed.

General Medicine · Fierce Healthcare · 14 Sept

Rhabdomyolysis Following Rapid Correction of Acute Hyponatraemia in a Patient With Psychogenic Polydipsia

Serum sodium rose from 117 mmol/L to 131 mmol/L within six hours; CK was already elevated on admission and peaked at 60,672 U/L, with preserved renal function.

General Medicine · Cureus · 14 Sept

India may get own dengue vax by next year end: ICMR DG

A single-dose indigenous vaccine covering all four serotypes could reach Indian clinics by late 2026, but low case counts may delay trial unblinding.

General Medicine · ETHealthworld · 14 Sept

Global nutrition experts back FSSAI warning labels, seek stricter rules

Stricter front-of-pack warnings on high sugar, salt and saturated fat could make packaged-food counselling easier for patients with diabetes, hypertension and obesity.

General Medicine · ETHealthworld · 14 Sept

Pneumococcal population structure influences the effects of air pollution on invasive disease risk in South Africa.

Air pollution raises invasive pneumococcal disease risk unevenly across serotypes, so vaccinating high-risk patients matters more on bad-air days.

General Medicine · Nature microbiology · 14 Sept

Most-favoured-nation pricing for prescription drugs in US Medicare: a cohort study.

US Medicare MFN rebates could reset global reference prices, indirectly squeezing Indian drug supply and pricing for the medicines you prescribe.

General Medicine · Lancet · 13 Sept

Quantifying Diagnostic Misclassification and Inpatient Mortality Determinants in Scrub Typhus: A Systematic Review and Interaction Meta-Analysis of Acute Undifferentiated Febrile Illness (AUFI) Cohorts in India

Pooled scrub typhus prevalence 14.60% (95% CI 11.27-18.71); high-rigor assays 17.40% versus rapid ICT or Weil-Felix 11.90% (p = 0.024); pooled inpatient mortality 4.92% (95% CI 2.98-7.95)

General Medicine · Cureus · 12 Sept

Granulomatous Interstitial Nephritis Associated With Adalimumab Therapy in a Patient With Rheumatoid Arthritis: A Case Report

Renal biopsy showed granulomatous interstitial nephritis. Adalimumab was stopped and steroids started; kidney function improved.

General Medicine · Cureus · 12 Sept

Shared Decision-Making and Decision Support in Advanced Chronic Kidney Disease: A Systematic Review of Models, Treatment Pathways, and Patient-Centered Outcomes

Structured decision aids for dialysis-versus-conservative-care choices may improve modality selection and patient-reported outcomes; this review maps which models have evidence behind them.

General Medicine · Cureus · 12 Sept

Efficacy and safety of mitapivat in adults with transfusion-dependent α-thalassaemia or β-thalassaemia (ENERGIZE-T): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial.

Transfusion reduction response occurred in 52 (30%) of 171 on mitapivat versus 11 (13%) of 87 on placebo; adjusted difference 18 percentage points (95% CI 8-27; p=0·0003).

General Medicine · Lancet · 12 Sept

PHTI report finds limited impact from virtual kidney care solutions, prompting industry pushback

Before referring CKD patients to virtual kidney programmes, note this review found limited evidence of benefit, though vendors dispute the methodology.

General Medicine · Fierce Healthcare · 11 Sept

A Structured, Auditable Taxonomy for Pharmacist-Identifiable Medication-Related Risk Signals in Routine Admission Data: A Retrospective Medication Safety Audit in a High-Risk Inpatient Cohort

Poor adherence 10 of 17; residual medication discrepancy 5 of 17; self-discontinuation 3 of 17; insulin instruction mismatch 2 of 17; suboptimal blood pressure control 9 of 13; suboptimal glycaemic control 5 of 8.

General Medicine · Cureus · 11 Sept

Mpox (Formerly Known as Monkeypox) in Dermatological Practice: Presentation of a Series of Four Clinical Cases at a Referral Hospital

Presentations ranged from disseminated vesiculopustular eruptions with systemic symptoms to strictly localised painful perianal lesions without prodrome; one case was initially misdiagnosed as herpes.

General Medicine · Cureus · 11 Sept

Unusual Vascular Claudication in a Seronegative Patient: Raynaud's Phenomenon or Atypical Buerger Disease

Proximal vessels were patent with sluggish distal forearm flow and diminutive radial and ulnar arteries at the wrist; hypercoagulable and vasculitis workup was unrevealing and inflammatory markers stayed normal.

General Medicine · Cureus · 11 Sept

Oral Health in Hospitalized Adults: Clinical Outcomes and the Role of Dental Expertise

Strongest evidence is for respiratory outcomes; recent randomised evidence gives preliminary support for structured multicomponent oral care reducing non-ventilator hospital-acquired pneumonia on general wards. Chlorhexidine evidence remains inconsistent.

General Medicine · Cureus · 11 Sept

Disseminated Pulmonary Coccidioidomycosis Presenting as a Wedge-Shaped Necrotic Mass Mimicking Malignancy

CT showed a 7.3 × 5.4 cm wedge-shaped necrotic right middle lobe mass with bilateral nodules; biopsy showed granulomatous inflammation with fungal elements, confirmed by serology and BAL PCR

General Medicine · Cureus · 11 Sept

STAT+: Can AI save rural health care?

Federal bets on AI for rural care may shape what tools reach your understaffed district hospital, though none are proven yet.

General Medicine · STAT News — Health Tech · 10 Sept

Clinical and Radiographic Success of Pulpotomy in Permanent Teeth With Irreversible Pulpitis: A Systematic Review

Across 16 included studies, pulpotomy consistently gave favourable clinical and radiographic success in permanent teeth with irreversible pulpitis, especially with MTA, Biodentine, CEM and other bioceramics.

General Medicine · Cureus · 10 Sept