Archive

Double-Vessel Involvement: A Case Report of Simultaneous Left Anterior Descending Artery (LAD) and Right Coronary Artery (RCA) Spontaneous Coronary Artery Dissection Causing Acute Coronary Syndrome

Angiography confirmed spontaneous coronary artery dissection in both the left anterior descending artery and right coronary artery, with moderate ischemic cardiomyopathy, an apical clot, and subclavian artery occlusion suggesting vasculitis

Cardiology · Cureus · 29 Sept

Atrial Fibrillation in Tribal and Non-tribal Populations: A Comparative Analysis From Eastern India

Tribal AF patients in eastern India may differ in rheumatic vs cardiometabolic drivers and anticoagulation uptake, so check whether your tribal patients are being anticoagulated to the same standard.

Cardiology · Cureus · 29 Sept

Complete Heart Block in Young Patient With Systemic Lupus Erythematosus: A Case Report

In young SLE patients, screen for conduction disease with baseline ECG even without syncope, since complete heart block can be asymptomatic and need pacing.

Cardiology · Cureus · 28 Sept

Fat Emboli Entrapped in the Tricuspid Valve Chordae Following Autologous Fat Grafting: An Echocardiographic-Pathological Correlation

Fat embolism after lipofilling can cause cardiac arrest in healthy young patients; echocardiography showing tricuspid chordae entrapment may aid post-mortem and antemortem diagnosis.

Cardiology · Cureus · 28 Sept

Reverse Takotsubo Cardiomyopathy Complicated by Neurogenic Pulmonary Edema in Aneurysmal Subarachnoid Hemorrhage: A Case Report

In aSAH, basal hypokinesis with apical sparing plus neurogenic pulmonary edema can mimic acute MI; recognise it to avoid inappropriate thrombolysis or angiography.

Cardiology · Cureus · 28 Sept

Diagnostic Challenges of Regional Cardiac Tamponade in a Severely Volume-Overloaded Dialysis Patient: The Role of Multimodality Imaging

In dialysis patients with unexplained tachycardia, regional tamponade can hide without classic echo signs; multimodality imaging is needed before attributing it to volume overload.

Cardiology · Cureus · 28 Sept

Prevalence and Clinical Characteristics of Myocardial Infarction With Non-obstructive Coronary Arteries Compared With Obstructive Myocardial Infarction: A Retrospective Tertiary-Centre Study

MINOCA was 2.9% of MIs. MINOCA patients were younger (52.1 vs 59.8 years; p=0.005) and more often presented as NSTEMI (51.4% vs 13.9%; p<0.001).

Cardiology · Cureus · 28 Sept

A metabolic-epigenetic switch governs multicellular cardiac repair following succinate dehydrogenase inhibition.

Malonate, an already-usable SDH inhibitor, drove multicellular repair after MI in animals; if replicated, it points to a metabolic route to cardiac regeneration.

Cardiology · Nature cardiovascular research · 28 Sept

Therapeutic upregulation of gene expression in inherited cardiomyopathies from current approaches to future directions.

For haploinsufficiency-driven cardiomyopathy, raising output from the remaining healthy allele is a plausible route to disease-modifying therapy rather than symptom control.

Cardiology · Nature cardiovascular research · 28 Sept

Prognostic Value of Conventional Echocardiographic Parameters of Right Ventricular Dysfunction in a Real-World Cohort of Patients With Acute Pulmonary Embolism

TAPSE, S' and RV FAC showed no correlation with PESI (p = 0.084, 0.235, 0.637) or mortality (p > 0.05). RV FAC <35% linked to PESI class (p = 0.026) but failed correction. Mortality 12.5%.

Cardiology · Cureus · 27 Sept

Large, Life-Threatening Right Ventricular and Pulmonary Artery Thrombus Revealing Antiphospholipid Syndrome: The Role of Risk Stratification and Thrombolytic Therapy

In intermediate-risk PE with a large right ventricular thrombus, risk stratification plus thrombolysis can avert sudden haemodynamic collapse, and antiphospholipid syndrome should be excluded.

Cardiology · Cureus · 27 Sept

Beyond Digoxin Toxicity: A Fatal Case of BRASH Syndrome Triggered by Community-Acquired Pneumonia

In a bradycardic, hyperkalaemic, shocked patient on AV nodal blockers, think BRASH syndrome — the fix is stopping the drug and correcting potassium, not pacing.

Cardiology · Cureus · 27 Sept

Ticagrelor-Induced Bradyarrhythmias in Acute Coronary Syndrome: A Case Series of Three Patients

All three developed high-grade AV block, asystole or cardiac arrest after ticagrelor; two recovered after switching to prasugrel, one needed a permanent pacemaker. Naranjo rated the association possible in each.

Cardiology · Cureus · 25 Sept

Redesigning cardiovascular medicine around sex differences.

Women's cardiovascular risk and presentation differ from men's; the evidence base you rely on was built mostly in men, so diagnostic thresholds and treatments may not fit your female patients.

Cardiology · Nature Medicine · 25 Sept

Cardiac proteomic and phosphoproteomic profiling defines clinically relevant molecular subgroups in human heart failure.

Etiology-stratified analyses showed convergence to a shared end-stage proteomic landscape, but unbiased proteome-based clustering identified two molecular subgroups with divergent fibrosis and immune infiltration; subgrouping proteins also predicted survival in an independent plasma cohort.

Cardiology · Nature cardiovascular research · 25 Sept

Diverse Clinical Spectrum of TTN-Truncation Variant Cardiomyopathy: A Case Series Illustrating Asymptomatic, Arrhythmic, Recurrent Takotsubo, and Inflammatory Phenotypes

Four cases: asymptomatic moderate LV systolic dysfunction found on screening; ventricular tachycardia storm needing multiple ablations and ICD shocks; two discrete takotsubo episodes; FDG-PET myocardial inflammation responding to corticosteroids

Cardiology · Cureus · 25 Sept

Left Inferior Pulmonary Vein Thrombosis and Secondary Lung Infarction Following Radiofrequency Catheter Ablation: A Diagnostic Challenge

Initial CT angiography read as isolated alveolar hemorrhage; repeat imaging at day 31 showed complete left inferior pulmonary vein thrombosis with secondary pulmonary infarction.

Cardiology · Cureus · 24 Sept

Clinical Performance and Safety of the Optima Non-compliant Percutaneous Transluminal Coronary Angioplasty Balloon in Contemporary Percutaneous Coronary Intervention: A Multicenter Real-World Study

Real-world multicentre data on a high-pressure NC balloon give you procedural success and short-term safety figures to weigh when choosing lesion preparation and stent optimisation devices.

Cardiology · Cureus · 24 Sept

First Presentation With Impending Cardiac Tamponade Leading to a New Diagnosis of Mediastinal Lymphoma: A Shared Learning Case on the Atypical Presentation of Pericardial Effusion and Cardiac Tamponade

A young woman with dyspnoea and oedema but no full Beck's triad had tamponade from undiagnosed mediastinal lymphoma; keep effusion on the differential when the classic signs are absent.

Cardiology · Cureus · 24 Sept

Gut microbiome shifts in chronic systolic heart failure are associated with disease severity and clinical improvement.

Microbiome composition tracked HF severity and clinical improvement, hinting at gut-derived targets or markers, but this is early mechanistic work with no therapy ready for patients.

Cardiology · Nature cardiovascular research · 24 Sept

Clinical and Echocardiographic Characterization of Stage B Heart Failure in Asymptomatic Adults With Cardiovascular Risk Factors

Nearly all asymptomatic at-risk adults had echo abnormalities, so screening echocardiography in patients with hypertension or diabetes may catch pre-HF before symptoms.

Cardiology · Cureus · 23 Sept

Clinical and Biochemical Responses to SGLT2 (Sodium-Glucose Cotransporter-2) Inhibitors in Patients With Rheumatic Heart Disease and Heart Failure

Adds Indian data on SGLT2 inhibitors in rheumatic heart disease heart failure, a group usually excluded from the landmark trials you rely on.

Cardiology · Cureus · 23 Sept

Vascular aging as a driver of organ dysfunction and systemic aging.

No primary outcome or effect size reported. Authors argue endothelial and mural cells instruct organ function via angiocrine and paracrine signalling, making microvascular aging a driver rather than a bystander.

Cardiology · Nature cardiovascular research · 23 Sept

Graves’ Disease and the Heart: Severe Reversible Left Ventricular Systolic Dysfunction With Apical Thrombus in a Young Woman With Relapsed Thyrotoxicosis

In young thyrotoxic patients with unexplained LV dysfunction, consider Graves' cardiomyopathy with apical thrombus — antithyroid therapy plus anticoagulation can fully reverse it.

Cardiology · Cureus · 23 Sept

Kidney Outcomes in Structural Heart and Cardiac Surgical Trials: The Case for Longitudinal Endpoint Reporting

Cardiac trial reports you rely on often omit longitudinal kidney outcomes, so post-procedure renal risk in your valve and surgical patients stays under-recognised.

Cardiology · Cureus · 22 Sept

Occurrence of Heart Failure-Related Clinical Signs in a Japanese Convalescent Rehabilitation Ward: A Cross-Sectional Pilot Study

HF signs are common in rehab inpatients and often missed; screen for them before attributing breathlessness or fatigue to deconditioning.

Cardiology · Cureus · 22 Sept

Cordis’ sirolimus drug-coated balloon earns FDA approval as a breakthrough device

A sirolimus-coated balloon now offers an alternative to repeat stenting for coronary in-stent restenosis, though Indian access and cost remain uncertain.

Cardiology · Fierce Biotech · 22 Sept

Glycyrrhizin-Induced Pseudoaldosteronism Contributing to Decompensated Heart Failure With Preserved Ejection Fraction

Ask heart failure patients about licorice and kampo preparations; stopping the culprit corrects hypokalemia and hypertension without diuretic escalation.

Cardiology · Cureus · 22 Sept

Proteome-wide genetic analyses identify ASGR1 as a potential biomarker linking smoking with ischemic heart disease.

ASGR1 may be the mediator between smoking and coronary disease, hinting at a target for risk stratification in smokers beyond standard risk factors.

Cardiology · Nature cardiovascular research · 22 Sept

Bioadaptive spatiotemporal nanomedicine promotes metabolic recovery after myocardial infarction through NAD(+) and UCP2 regulation.

Preclinical only: staged NAD+ release restored mitochondrial metabolism and limited remodeling in mice, so watch for human dosing and delivery data before it touches post-MI care.

Cardiology · Nature cardiovascular research · 22 Sept

Peripheral arterial disease: adverse impacts, disparities in outcomes, and the path ahead.

PAD affects over 300 million people worldwide, causing chronic pain, functional limitation, amputation, myocardial infarction, stroke and death, with burden concentrated in underserved groups.

Cardiology · Lancet · 22 Sept

Current advancements in the care of peripheral arterial disease: modern approaches to medical, endovascular, and surgical treatment.

Amputation risk is low in asymptomatic PAD and intermittent claudication, with only a few progressing to chronic limb threatening ischaemia; supervised exercise improves walking capacity and avoids revascularisation risks

Cardiology · Lancet · 22 Sept

Early Post-transcatheter Aortic Valve Implantation (TAVI) Haemodynamics With SAPIEN Balloon-Expandable and Evolut Self-Expanding Valve Platforms: A Retrospective Single-Centre Cohort Study

Valve choice at TAVI affects early gradients, so knowing how SAPIEN and Evolut differ helps you anticipate haemodynamics and follow-up echo findings.

Cardiology · Cureus · 22 Sept

Late-Onset Prosthetic Valve Dysfunction Associated With Hypoattenuated Leaflet Thickening Detected After a New Heart Murmur: A Case Report

A new murmur after sutureless bioprosthetic AVR may signal HALT; consider CT to detect leaflet thickening before overt valve failure develops.

Cardiology · Cureus · 22 Sept

Enhancing Inpatient Echocardiogram Request Appropriateness and Timeliness Using British Society of Echocardiography Guidelines: A Quality Improvement Project

Appropriate requests rose from 82/100 (82%) to 90/100 (90%), an absolute change of 8 percentage points (95% CI −1.7 to +17.8; p=0.153). Completion within 24 hours changed from 77/100 (77%) to 79/100 (79%).

Cardiology · Cureus · 21 Sept

The Dangers of Chest Compression: A Case Report

Post-CPR sternal and rib fractures can seed infected parasternal collections; consider this in resuscitated patients with persistent chest pain or fever.

Cardiology · Cureus · 20 Sept

Myocarditis Revealing a Pathogenic Desmoplakin (DSP) Variant: Implications for Genetic Testing Pathways

In young myocarditis patients, especially with a family history, consider desmoplakin testing — a positive result reframes this as arrhythmogenic cardiomyopathy needing lifelong surveillance.

Cardiology · Cureus · 20 Sept

New Statin-Safety Reassurance: How Far Can It Extend to South Asian Patients?

Statin safety data from Western cohorts may not transfer to South Asian patients, whose differing pharmacokinetics could alter myopathy and intolerance risk at standard doses.

Cardiology · Cureus · 19 Sept

Minimally Invasive Coronary Artery Bypass Grafting for Predominantly Multivessel Coronary Artery Disease: Early Perioperative Outcomes of 149 Patients

Adds single-centre evidence that multivessel MICS-CABG avoids sternotomy with acceptable early outcomes, though results remain confined to high-volume specialised centres.

Cardiology · Cureus · 19 Sept

Unmasking Brugada Syndrome With Oral Propafenone in a Resource-Limited Setting: A Case Report

Oral propafenone can unmask type 1 Brugada patterns where IV ajmaline or flecainide is unavailable, letting you confirm the diagnosis before a fatal arrhythmia does.

Cardiology · Cureus · 18 Sept